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https://www.researchgate.net/publication/260361350_Alginate_microparticles_for_biodelivery_A_review
alginate and a chitosan presents a valuable source of delivery of living bact erial cells to t he colon and keeping their viability in simulated gastr ic and intestinal juice.
https://www.sciencedirect.com/science/article/pii/S0144861717302898
The increase in the research interest on alginate microparticles in pharmaceutical and biomedical areas confirms its potential use as an effective matrix for drug and cell delivery. Among the well known alginate properties, pH sensitivity remains as an attractive option for …Author: Lissette Agüero, Dionisio Zaldivar-Silva, Luis Peña, Marcos L. Dias
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481983/
Aug 12, 2012 · Alginate-based materials have received considerable attention for biomedical applications because of their hydrophilic nature, biocompatibility, and physical architecture. Applications include cell encapsulation, drug delivery, stem cell culture, and …Author: Omaditya Khanna, Jeffery C. Larson, Monica L. Moya, Emmanuel C. Opara, Eric M. Brey, Eric M. Brey
https://www.sciencedirect.com/science/article/pii/S0939641112000392
The aim of this study was to prepare novel Zn 2+ -cross-linked alginate microparticles for controlled pulmonary delivery of protein drugs via a simple one-step spray-drying process and to physicochemically characterize these systems.Author: Katrin Möbus, Jürgen Siepmann, Roland Bodmeier
https://www.sciencedirect.com/science/article/pii/S0939641116302648
Biopolymer-based aerogels with mucoadhesive properties are of special interest for pharmaceutical applications as they can be designed for administration through various mucosal delivery routes (nasal, buccal, intestinal and vaginal). This paper presents a first attempt towards aerogel microparticles for mucosal drug delivery.Author: V.S.S. Gonçalves, V.S.S. Gonçalves, P. Gurikov, J. Poejo, A.A. Matias, S. Heinrich, C.M.M. Duarte, I...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603011/
BSA loaded chitosan microparticles suspensions with pH value at 5.1 were added dropwisely into sodium alginate solution (pH = 7.2) at concentration of 10 mg/ml under mild agitation for 10 min. Then the suspension was centrifuged at 3,400 rpm for 5 min, and the supernatant was discarded.Author: XingYi Li, XiangYe Kong, Shuai Shi, XiuLing Zheng, Gang Guo, YuQuan Wei, ZhiYong Qian
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004034/
The present review overviews the most relevant applications of alginate microparticles and nanoparticles for drug administration by the oral route and discusses the perspectives of this biomaterial in the future.Author: Alejandro Sosnik
https://www.sciencedirect.com/science/article/pii/B9780128003503000042
Alginate is a biodegradable polymer that can be used for the formation of nanospheres with applications in food, biomedicine, and biotechnology. Alginate gels in mild conditions, and does not require organic solvents for the formation of nanospheres.Author: Jerome P. Paques
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223967/
Alginate is a naturally occurring anionic polymer typically obtained from brown seaweed, and has been extensively investigated and used for many biomedical applications, due to its biocompatibility, low toxicity, relatively low cost, and mild gelation by addition of divalent cations such as Ca 2+ [ 4 ].Author: Kuen Yong Lee, David J. Mooney
https://www.sciencedirect.com/science/article/pii/S0001868614001341
In this review, the focus will be on the formation of alginate nanoparticles. First some general chemical and physical properties of alginate and different types of alginate bulk gels are discussed. This is followed with a brief overview of methods to prepare alginate microparticles.Author: Jerome P. Paques, Erik van der Linden, Cees J.M. van Rijn, Leonard M.C. Sagis
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