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https://www.tandfonline.com/doi/full/10.1081/DDC-120003853
Feb 13, 2017 · The drug delivery systems should contain a mucoadhesive component that binds to mucin. It appears that polyanions, especially polymers containing carboxylic groups and with a high charge density, are highly active. Alginate is demonstrated to have excellent bioadhesive properties.Author: Hanne Hjorth Tønnesen, Jan Karlsen
https://www.ncbi.nlm.nih.gov/pubmed/12149954/
The conventional use of alginate as an excipient in drug products generally depends on the thickening, gel-forming, and stabilizing properties. A need for prolonged and better control of drug administration has increased the demand for tailor-made polymers.Author: Hanne Hjorth Tønnesen, Jan Karlsen
https://www.tandfonline.com/doi/pdf/10.1081/DDC-120003853
significant role in the design of a controlled-release product. At low pH hydration. of alginic acid leads to the formation of a high-viscosity ‘‘acid gel.’’ Alginate is. also easily gelled in the presence of a divalent cation as the calcium ion.
https://www.researchgate.net/publication/11232706_Alginate_in_Drug_Delivery_Systems
Alginates have a wide application as rate-controlling excipient in drug delivery systems, as an excipient in pharmaceutical preparations for local application and as a matrix for biomolecules [18 ...
https://pharmahub.org/resources/534/download/Alginate_Bead_Experiment.pdf
detect a solid alginate in the liquid. Drug Delivery . Controlled drug delivery is a field dedicated to the release of therapeutically active agents into the body. Drug delivery is an important part of the pharmaceutical aspect of chemical engineering. Although it is the chemists and pharmacists job to combine the chemicalsFile Size: 165KB
https://www.researchgate.net/publication/286661633_Alginate_in_controlled_drug_delivery_systems
Controlled drug delivery systems frequently offer significant benefit in comparison with immediate release dosage forms from the efficiency and safety viewpoint. Controlled release can be achieved using various polymers. Alginate is naturally occurring polysaccharide extracted from kelp.
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