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https://www.slideshare.net/optimpharma/bio-adhesive-drug-delivery-system
Mar 01, 2012 · Bio/muco-adhesive systems: bind to the gastric epithelial cell surface or mucin, which extends the GRT of drug delivery system in the stomach. The ability to provide adhesion of a drug delivery system to the gastrointestinal wall provides longer residence time in a particular organ site, thereby producing an improved effect in terms of local ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Gastrointestinal Mucoadhesive Drug Delivery Systems. Oral route is undoubtedly most favored route of administration, but hepatic first-pass metabolism, degradation of drug during absorption, mucus covering GI epithilia, and high turnover of mucus are serious concerns of oral route.
https://www.researchgate.net/publication/317637304_Bioadhesive_drug_delivery_systems_Overview_and_recent_advances
Bio adhesive systems have gained growing interest due to its ability to localize the drug delivery along with sustained release. This leads to reduction of side-effects due to non-specific targeting.Author: Devarshi Brahmbhatt
https://www.adhesivesmag.com/articles/86012-adhesives-in-transdermal-drug-delivery-systems
Nov 01, 2005 · In liquid reservoir systems, the drug must pass through the adhesive layer, so precautions must be taken to ensure that the drug and adhesive do not react with each other. A variation of the liquid reservoir system is the polymer matrix system.
https://www.sciencedirect.com/science/article/pii/S1461534799001194
Adhesives are a critical component in transdermal drug delivery (TDD) devices. In addition to the usual requirements of functional adhesive properties, adhesives for TDD applications must have good biocompatibility with the skin, chemical compatibility with the drug, various components of the formulation, and provide consistent, effective delivery of the drug.Author: Hock S Tan, William R Pfister
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems have applications from different angles, including development of novel mucoadhesives, design of the device, mechanisms of mucoadhesion and permeation enhancement. With the influx of a large number of new drug molecules due to drug discovery, mucoadhesive drug delivery will play an even more important role in ...
https://www.henkel-adhesives.com/us/en/industries/medical/drug-delivery-polymers.html
Advanced Adhesive Solutions for Drug Delivery Systems. Henkel has been an integral part of the transdermal market since its inception. As a global leader in acrylic polymers for transdermal drug delivery, Henkel’s Duro-Tak and Gelva pressure sensitive adhesives are approved in over 50 unique commercial patches marketed in the Americas, Australia, China, Europe, India, Japan and Korea.
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