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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900005/
Jan 01, 2014 · With thousands of articles published regarding adenovirus vectors, and hundreds of human trials with adenovirus vectors, what have we learned and what is the role of adenovirus vectors in the gene therapist's armamentarium? First, there is no question that the adenovirus is the most effective means of delivering genes in vivo.Author: Ronald G. Crystal
https://www.liebertpub.com/doi/10.1089/hum.2019.127
Dec 16, 2019 · However, gene delivery to kidney cells is inefficient. This is due, in part, to the fact that the kidney excludes molecules above 50 kDa and that most gene delivery vectors are megaDaltons in mass. We compared the ability of adeno-associated virus (AAV), adenovirus (Ad), and lentiviral (LV) vectors to deliver genes to renal cells.Author: Jeffrey D. Rubin, Tien V. Nguyen, Kari L. Allen, Katayoun Ayasoufi, Michael A. Barry
https://www.sciencedirect.com/science/article/pii/S2352304217300272
Among all currently available viral vectors, adenovirus is the most efficient gene delivery system in a broad range of cell and tissue types. The applications of adenoviral vectors in gene delivery have greatly increased in number and efficiency since their initial development.Author: Cody S. Lee, Elliot S. Bishop, Ruyi Zhang, Ruyi Zhang, Xinyi Yu, Xinyi Yu, Evan M. Farina, Shujuan Y...
https://www.sciencedirect.com/topics/medicine-and-dentistry/adenovirus-vector
B.K. Kaspar, in Encyclopedia of Neuroscience, 2009. Adenoviral. Adenoviral vectors have been one of the most widely used viruses in gene delivery. They are nonenveloped, double-stranded (ds) DNA viral vectors with a packaging capacity of approximately 35 kb.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927556/
Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in developing clinically desirable AAV capsids, optimizing genome designs and harnessing revolutionary biotechnologies have contributed substantially to the growth of the gene therapy field.Author: Dan Wang, Phillip W. L. Tai, Guangping Gao
https://www.nature.com/articles/s41573-019-0012-9
Feb 01, 2019 · Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in …Author: Dan Wang, Phillip W. L. Tai, Guangping Gao
https://www.nejm.org/doi/full/10.1056/NEJM199605023341809
Molecular Medicine from The New England Journal of Medicine — Adenoviruses as Gene-Delivery Vehicles. ... of genes as therapy requires vehicles —so-called vectors — that encapsulate the gene ...Author: James M. Wilson
https://www.pnas.org/content/104/8/2596
Feb 20, 2007 · Thus, the unique mode of gene delivery by adenovirus vectors complements previously established genetic manipulation methods that achieve stable germ-line integration and will provide new opportunities for studies on male germ cell biology. Materials and Methods. Recombinant Adenovirus.Author: Masanori Takehashi, Mito Kanatsu-Shinohara, Kimiko Inoue, Narumi Ogonuki, Hiromi Miki, Shinya Toyoku...
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