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https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.13098
Active targeting is able to significantly increase the quantity of drug delivered to the target cell compared to free drug or passively targeted nanosystems. After accumulation in the tumour region, the drug efficiency can be even increased by the so‐called active targeting.Author: Mohamed F. Attia, Mohamed F. Attia, Nicolas Anton, Justine Wallyn, Ziad Omran, Thierry F. Vandamme
https://www.medscape.com/viewarticle/770397_3
Nov 06, 2019 · Targeting Strategies . Two basic requirements should be realized in the design of nanocarriers to achieve effective drug delivery (Figure 2). First, drugs should be able to …
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/targeted-drug-delivery
7 Nanoparticles for Cancer Drug Delivery: Active versus Passive Targeting. Targeted drug delivery by conjugating with a biocompatible polymer allowing better solubility, lower toxicity, and prolonged release forms the basis of cancer medicine. In the past few decades unprecedented endeavors have been made in the development of nanomaterials ...
https://link.springer.com/chapter/10.1007%2F978-3-642-00477-3_1
Nov 19, 2009 · Drug carriers are expected to stay in the blood for long time, accumulate in pathological sites with affected and leaky vasculature (tumors, inflammations, and infarcted areas) via the enhanced permeability and retention (EPR) effect, and facilitate targeted delivery of specific ligand-modified drugs and drug carriers into poorly accessible areas.Author: Vladimir P. Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179822/
Jul 23, 2014 · There are two ways by which targeting of nanoparticles may be achieved, namely passive and active targeting. The aim of this study was to provide a comprehensive review of the literature focusing on passive targeting. ... Passive and active drug targeting: drug delivery to tumors as an example. Handb Exp Pharmacol. 2010; 197:3–53. 47.Author: Remon Bazak, Mohamad Houri, Samar El Achy, Wael Hussein, Tamer Refaat
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038858/
Jul 04, 2018 · For a few decades, nanoparticles have been developed as a drug delivery system of various chemotherapeutic drugs to enhance drug efficacy and safety.2–4 Nanoparticles play an important role in increasing drug concentration in cancer cells by enhancing drug accumulation by passive and active targeting mechanisms as well as by decreasing drug ...Author: Nadda Muhamad, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang
https://www.researchgate.net/publication/260643363_Recent_Advances_in_Active_Hepatic_Targeting_Drug_Delivery_System
Recent Advances in Active Hepatic Targeting Drug Delivery System ... of active hepatic targeting drug/gene delivery systems for the treatment of hepatic diseases that were mediated by some kinds ...
https://www.sciencedirect.com/science/article/pii/S1369702105710336
Download : Download high-res image (560KB) Download : Download full-size image Fig. 1.Schematic of two different targeted nanoparticle drug delivery systems. (A) Liposomal-based systems are vesicular with targeting or PEG groups either preconjugated with a lipid then formed into a vesicle or postinserted into the liposome.Author: Tarek M. Fahmy, Peter M. Fong, Amit Goyal, W. Mark Saltzman
https://www.researchgate.net/publication/41850483_Passive_and_Active_Drug_Targeting_Drug_Delivery_to_Tumors_as_an_Example
In passive targeting, anatomical discrepancies between the normal tissue and the overtaken tissue are exploited for drug delivery [165]. Active targeting is achieved by identifying the ligand ...
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