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https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.13098
Active targeting is able to significantly increase the quantity of drug delivered to the target cell compared to free drug or passively targeted nanosystems. After accumulation in the tumour region, the drug efficiency can be even increased by the so‐called active targeting.Author: Mohamed F. Attia, Mohamed F. Attia, Nicolas Anton, Justine Wallyn, Ziad Omran, Thierry F. Vandamme
https://www.sciencedirect.com/science/article/pii/S0928493119312032
An active targeting drug delivery system can selectively penetrate tumor cells, enhance the therapeutic efficacy, and decrease the cytotoxicity and side effects ; hence, cell-specific targeting nanocarriers have become hotspots for tumor therapy [20,21].Author: Zehui He, Yongtai Zhang, Nianping Feng
http://www.americanpharmaceuticalreview.com/Featured-Articles/148744-Key-Targeting-Approaches-for-Pharmaceutical-Drug-Delivery/
Oct 25, 2013 · Active Targeting. Active targeting is a non-invasive approach, in which the drug is transported to the target organ or tissue using site-specific ligands. The pairing of drug carriers, such as liposome, particulate nanocarrier etc., with a ligand leads to the specific targeting to selected cells.
https://www.pharmatutor.org/articles/drug-targeting-basic-concepts-drug-carrier-systems-review
Target drug delivery system is a special form of drug delivery system where the pharmacologically active agent or medicament is selectively targeted or delivered only to its site of action or absorption and not to the non-target organs or tissues or cells.
https://pubs.rsc.org/en/content/articlelanding/2020/tb/d0tb00289e
Over the past decade, nanoparticle-based drug delivery systems have been extensively explored. However, the average tumour enrichment ratio of passive targeting systems corresponds to only 0.7% due to the nonspecific uptake by normal organs and poor selective retention in tumours. The therapeutic specificity and ef Journal of Materials Chemistry B Recent Review ArticlesAuthor: Yahui Zhang, Jing Cao, Zhi Yuan
https://link.springer.com/chapter/10.1007%2F978-3-642-00477-3_1
Nov 19, 2009 · Among various approaches to specifically target drug-loaded carrier systems to required pathological sites in the body, two seem to be most advanced – passive (EPR effect-mediated) targeting, based on the longevity of the pharmaceutical carrier in the blood and its accumulation in pathological sites with compromised vasculature, and active targeting, based on the attachment of specific …Author: Vladimir P. Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038858/
Jul 04, 2018 · Active targeting nanoparticles that are conjugated to targeting ligands on the surface of nanoparticles play an important role in improving drug selectivity to the cancer cell. Several chemotherapeutic drugs and traditional/herbal medicines reported for anticancer activities have been investigated for their selective delivery to cancer cells by active targeting nanoparticles.Author: Nadda Muhamad, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang
https://www.sciencedirect.com/science/article/pii/S1369702105710336
Nanoparticles are potentially useful as carriers of active drugs and, when coupled with targeting ligands, may fulfill many attributes of a ‘magic bullet’. This review focuses on targeted drug delivery using nanoparticles as a modality that couples a ligand to a nanosized,...Author: Tarek M. Fahmy, Peter M. Fong, Amit Goyal, W. Mark Saltzman
https://www.slideshare.net/anushanagraj/targeted-drug-delivery-system
Sep 11, 2014 · INTRODUCTION : ‘Targeted drug delivery system is a special form of drug delivery system where the medicament is selectively targeted or delivered only to its site of action or absorption and not to the non-target organs or tissues or cells.’
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