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https://en.wikipedia.org/wiki/Acoustic_targeted_drug_delivery
Sonodynamic therapy is a proposed form of treatment using drugs that only become cytotoxic upon exposure to ultrasound. Since ultrasound can be focused into small tissue volumes within the body, this method provides a potential means of localizing treatment and reducing the risk of toxic side-effects elsewhere in the body.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
Although this so-called “acoustic streaming” could enhance drug transport in vitro, we opine that it has little, if any application for in vivo systems because fluid convection in the vascular system is already very fast, ... Gene delivery is a topic of intense interest in targeted drug delivery [43 ...Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
https://www.youtube.com/watch?v=Z6BMYNXbwLU
Oct 21, 2015 · Using ultrasound waves, researchers have found a way to enable rapid delivery of drugs to the gastrointestinal (GI) tract. This approach could make it …
https://www.researchgate.net/publication/243527934_Acoustic_targeted_drug_delivery_in_neurological_tissue
Acoustic targeted drug delivery in neurological tissue Article in The Journal of the Acoustical Society of America 122(5) · November 2007 with 25 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S0924424719301396
A targeted drug delivery technology utilizing acoustic excitation of bubbles embedded in an electromagnetically actuated microrobot is proposed and experimentally verified. Two actuation schemes, electromagnetic actuation for driving the microrobot and acoustic bubble actuation for manipulating the drug are applied.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477603/
Jul 23, 2012 · Acoustic droplet vaporization of perfluorocarbon-loaded microbullets triggered by an ultrasound pulse provides the necessary force to penetrate, cleave, and deform cellular tissue for potential targeted drug delivery and precision nanosurgery.Author: Daniel Kagan, Michael J. Benchimol, Jonathan C. Claussen, Erdembileg Chuluun-Erdene, Sadik Esener, J...
https://www.sciencedirect.com/science/article/pii/S0378517315302489
In truth, the idea of targeted drug delivery currently remains essentially unresolved in medical practice. The authors propose a new concept enabling targeted delivery and/or localized enhanced uptake; Acoustic Cluster Therapy (ACT) ( Sontum et al., 2014 ).Author: Per Sontum, Svein Kvåle, Andrew John Healey, Roald Skurtveit, Rira Watanabe, Manabu Matsumura, Jonny...
https://asa.scitation.org/doi/10.1121/1.2942740
Using various acoustic pulse sequences we show a substantial increase in drug perfusion into brain mimicking tissue then can be achieved by diffusion alone. We are therefore able to reduce the time of delivery, the amount of drug delivered and the drugs local impact range.Author: George Lewis, William Olbricht
https://en.wikipedia.org/wiki/Sustained_Acoustic_Medicine
Delivering chemotherapy to brain cancer cells and various drugs to other tissues is called acoustic targeted drug delivery (ATDD). These procedures generally use high frequency ultrasound (1–10 MHz) and a range of intensities (0–20 W/cm 2).The acoustic energy is focused on the tissue of interest to agitate its matrix and make it more permeable for therapeutic drugs.
https://www.sciencedaily.com/releases/2018/03/180320084420.htm
Mar 20, 2018 · The concept represents a novel approach to targeted drug delivery and looks very promising," said Dr. Haiyong Han, a Professor in TGen's Molecular Medicine Division and head of the Basic Research ...
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