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https://www.pnas.org/content/110/6/2082
Feb 05, 2013 · Intracellular delivery of macromolecules is a challenge in research and therapeutic applications. Existing vector-based and physical methods have limitations, including their reliance on exogenous materials or electrical fields, which can lead to toxicity or off-target effects. We describe a microfluidic approach to delivery in which cells are mechanically deformed as they pass through a ...Author: Armon Sharei, Janet Zoldan, Andrea Adamo, Woo Young Sim, Nahyun Cho, Emily Jackson, Shirley Mao, Sab...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568376/
Feb 05, 2013 · Intracellular delivery of macromolecules is a critical step in therapeutic and research applications. Nanoparticle-mediated delivery of DNA and RNA, for example, is being explored for gene therapy (1, 2), while protein delivery is a promising means of affecting cellular function in both clinical and laboratory settings.Author: Armon Sharei, Janet Zoldan, Andrea Adamo, Woo Young Sim, Nahyun Cho, Emily Jackson, Shirley Mao, Sab...
https://www.ncbi.nlm.nih.gov/pubmed/23341631/
Feb 05, 2013 · A vector-free microfluidic platform for intracellular delivery. Sharei A(1), Zoldan J, Adamo A, Sim WY, Cho N, Jackson E, Mao S, Schneider S, Han MJ, Lytton-Jean A, Basto PA, Jhunjhunwala S, Lee J, Heller DA, Kang JW, Hartoularos GC, Kim KS, Anderson DG, Langer R, Jensen KF. ... Intracellular delivery of macromolecules is a challenge in ...Author: Armon Sharei, Janet Zoldan, Andrea Adamo, Woo Young Sim, Nahyun Cho, Emily Jackson, Shirley Mao, Sab...
https://www.pnas.org/content/early/2013/01/16/1218705110
Intracellular delivery of macromolecules is a challenge in research and therapeutic applications. Existing vector-based and physical methods have limitations, including their reliance on exogenous materials or electrical fields, which can lead to toxicity or off-target effects. We describe a microfluidic approach to delivery in which cells are mechanically deformed as they pass through a ...Author: Armon Sharei, Janet Zoldan, Andrea Adamo, Woo Young Sim, Nahyun Cho, Emily Jackson, Shirley Mao, Sab...
https://dspace.mit.edu/openaccess-disseminate/1721.1/80382
Intracellular delivery of macromolecules is a challenge in research and therapeutic applications. Existing vector-based and physical methods have limitations, including their reliance on exogenous materials or electrical fields, which can lead to toxicity or off-target effects.Author: Armon Sharei, Janet Zoldan, Andrea Adamo, Woo Young Sim, Nahyun Cho, Emily Jackson, Shirley Mao, Sab...
https://www.researchgate.net/publication/235363986_A_vector-free_microfluidic_platform_for_intracellular_delivery
A vector-free microfluidic platform for intracellular delivery Article (PDF Available) in Proceedings of the National Academy of Sciences 110(6) · January 2013 with 242 Reads How we measure 'reads'
http://sites.utexas.edu/texas-bmes/files/2015/07/2013-A-vector-free-microfluidic-platform-for-intracellular-delivery.pdf
A vector-free microfluidic platform for intracellular delivery Armon Shareia,b,1, Janet Zoldanb,1, Andrea Adamoa,1, Woo Young Sima, Nahyun Choa, Emily Jacksona, Shirley Maoa, ... Intracellular delivery of macromolecules is a challenge in research and therapeutic applications. Existing vector-based and …
https://dspace.mit.edu/handle/1721.1/81688
Cell squeezing : a vector-free microfluidic platform for intracellular delivery of macromolecules. Author(s) Sharei, Armon R. (Armon Reza) ... This dissertation describes a microfluidic approach to intracellular delivery that seeks to embody the advantages of a physical method, while mitigating issues related to toxicity and damage to the ...
https://www.nature.com/articles/nature19764
Oct 12, 2016 · Intracellular delivery of materials has become a critical component of genome-editing approaches, ex vivo cell-based therapies, and a diversity of …Author: Martin P. Stewart, Armon Sharei, Xiaoyun Ding, Gaurav Sahay, Robert Langer, Klavs F. Jensen
https://www.academia.edu/14626649/A_vector-free_microfluidic_platform_for_intracellular_delivery
A vector-free microfluidic platform for intracellular delivery
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