A Novel Intracellular Protein Delivery

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A novel intracellular protein delivery platform based on ...

    http://www.nature.com/articles/nnano.2009.341
    Nov 22, 2009 · We report a novel intracellular delivery platform based on nanocapsules that consist of a single-protein core and thin polymer shell anchored covalently to the protein core.

Frontiers Transdifferentiating Astrocytes Into Neurons ...

    https://www.frontiersin.org/articles/10.3389/fbioe.2018.00173/full
    Nov 21, 2018 · Transdifferentiating Astrocytes Into Neurons Using ASCL1 Functionalized With a Novel Intracellular Protein Delivery Technology. Meghan Robinson 1, Ian Fraser 1,2, Emily McKee 2, Kali Scheck 3, Lillian Chang 4 and Stephanie M. Willerth 1,2,5,6,7 * 1 Division of Medical Sciences, University of Victoria, Victoria, BC, Canada;Author: Meghan Robinson, Ian Fraser, Emily McKee, Kali Scheck, Lillian Chang, Stephanie M. Willerth

A novel intracellular protein delivery platform based on ...

    https://www.researchgate.net/profile/Zheng_Liu14/publication/40028951_A_novel_intracellular_protein_delivery_platform_based_on_single-protein_nanocapsules/links/541a5e330cf2218008bfb232.pdf
    We report a novel intracellular delivery platform based on nano-capsules that consist of a single-protein core and thin polymer shell anchored covalently to the protein core. As illustrated in Fig ...

Functionalizing Ascl1 with Novel Intracellular Protein ...

    https://www.ncbi.nlm.nih.gov/pubmed/27138845
    Functionalizing Ascl1 with Novel Intracellular Protein Delivery Technology for Promoting Neuronal Differentiation of Human Induced Pluripotent Stem Cells. Robinson M(1), Chapani P(2), Styan T(1), Vaidyanathan R(3), Willerth SM(4)(5)(6). Author information: (1)Biomedical Engineering Program, University of Victoria, Victoria, BC, Canada.Author: Meghan Robinson, Parv Chapani, Tara Styan, Ranjani Vaidyanathan, Stephanie Michelle Willerth

Intracellular Delivery of DNA and Protein by a Novel Cell ...

    https://www.ncbi.nlm.nih.gov/pubmed/32024261
    Feb 02, 2020 · Intracellular Delivery of DNA and Protein by a Novel Cell-Permeable Peptide Derived from DOT1L. ... Results indicate that CPP-Dot1l is a novel and effective CPP due to its good penetrating properties in different cell lines and its ability to enter cells in a concentration-dependent manner. Its penetration efficiency can be prompted by DMSO ...Author: Jingping Geng, Xiangli Guo, Lidan Wang, Richard Q. Nguyen, Fengqin Wang, Changbai Liu, Hu Wang

Novel Rath peptide for intracellular delivery of protein ...

    https://www.researchgate.net/publication/5506792_Novel_Rath_peptide_for_intracellular_delivery_of_protein_and_nucleic_acids
    Novel Rath peptide for intracellular delivery of protein and nucleic acids Article in Biochemical and Biophysical Research Communications 370(1):27-32 · June 2008 with 27 Reads How we measure 'reads'

Intracellular Delivery of DNA and Protein by a Novel Cell ...

    https://www.mdpi.com/2218-273X/10/2/217/htm
    Cellular uptake and intracellular release efficiency of biomacromolecules is low because of hurdles in the cell membrane that result in limited access to intra-cellular targets with few functional effects. Cell-penetrating peptides (CPPs) act as cargo delivery vehicles to promote therapeutic molecule translocation. Here, we describe the novel CPP-Dot1l that not only penetrates by itself, but ...Author: Jingping Geng, Xiangli Guo, Lidan Wang, Richard Q. Nguyen, Fengqin Wang, Changbai Liu, Hu Wang

Novel cell-penetrating peptide-adaptors effect ...

    https://jcs.biologists.org/content/129/5/893
    Mar 01, 2016 · The use of cell-penetrating peptides (CPPs) as biomolecular delivery vehicles holds great promise for therapeutic and other applications, but development has been stymied by poor delivery and lack of endosomal escape. We have developed a CPP-adaptor system capable of efficient intracellular delivery and endosomal escape of user-defined protein cargos. The cell-penetrating sequence of HIV ...Author: John C. Salerno, Verra M. Ngwa, Scott J. Nowak, Carol A. Chrestensen, Allison N. Healey, Jonathan L....

Silica Nanoparticles for Intracellular Protein Delivery: a ...

    https://nanoscalereslett.springeropen.com/articles/10.1186/s11671-017-2280-9
    Sep 25, 2017 · In this study, a novel approach for preparation of green fluorescent protein (GFP)-doped silica nanoparticles with a narrow size distribution is presented. GFP was chosen as a model protein due to its autofluorescence. Protein-doped nanoparticles have a high application potential in the field of intracellular protein delivery. In addition, fluorescently labelled particles can be used for ...Author: Sarah Schmidt, Isabella Tavernaro, Christian Cavelius, Eva Weber, Alexander Kümper, Carmen Schmitz, ...

Novel Rath peptide for intracellular delivery of protein ...

    https://www.sciencedirect.com/science/article/pii/S0006291X08004506
    May 23, 2008 · Novel Rath peptide for intracellular delivery of protein and nucleic acids. ... For intracellular delivery of other cargo molecules, the preformed complex was made. Approximately, to 100 μl of PBS (pH 7.2) the peptide was added first with subsequent addition of respective oligonucleotide/antibody or plasmid and incubated for 20–30 min at 37 ...Author: Manish V. Bais, Manish V. Bais, Satish Kumar, Ashok K. Tiwari, Ranjit S. Kataria, Viswas K. Nagaleek...

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