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https://www.ncbi.nlm.nih.gov/pubmed/17484139
1. Pharm Dev Technol. 2007;12(1):1-10. A critical review of gastric retentive controlled drug delivery. Waterman KC(1). Author information: (1)Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA. [email protected] The promise of gastric retentive drug delivery systems has propagated numerous investigations and the formation of a number of companies.Author: Kenneth C. Waterman
https://www.researchgate.net/publication/6347526_A_Critical_Review_of_Gastric_Retentive_Controlled_Drug_Delivery
A Critical Review of Gastric Retentive Controlled Drug Delivery Article · Literature Review in Pharmaceutical Development and Technology 12(1):1-10 · February 2007 with 66 Reads
https://www.tandfonline.com/doi/abs/10.1080/10837450601168680
Apr 11, 2004 · The promise of gastric retentive drug delivery systems has propagated numerous investigations and the formation of a number of companies. Three technologies have involved a substantial number of human clinical trials: mucoadhesion, density modification, and expansion. Standard, nondisintegrating controlled-release tablets can display significant gastric retention times, …Author: Kenneth C. Waterman
https://www.researchgate.net/profile/Moji_Adeyeye/publication/50373742_Gastroretentive_Floating_Drug-Delivery_Systems_A_Critical_Review/links/5559c87608ae6943a876e6bb.pdf
Gastroretentive Floating Drug-Delivery Systems: A Critical Review ... ing the gastric retention of a dosage form, including GRDDS, have been reported in the ... of novel controlled-release drug ...
https://www.sciencedirect.com/science/article/pii/S1818087616300320
Gastro-retentive drug delivery system (GRDDS) has gained immense popularity in the field of oral drug delivery recently. It is a widely employed approach to retain the dosage form in the stomach for an extended period of time and release the drug slowly that can address many challenges associated with conventional oral delivery, including poor bioavailability.Author: Uttam Kumar Mandal, Bappaditya Chatterjee, Faria Gias Senjoti
https://www.semanticscholar.org/paper/ON-GASTRO-RETENTIVE-DRUG-DELIVERY-SYSTEM-Kumar-Satyanarayana/34c4cf8f79eb3c7d67782ba25d6d885c35910061
Purpose of this review is to compile the recent literature with special focus on various gastro retentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. In order to understand various physiological difficulties to achieve gastric retention, we have ...
https://stm.sciencemag.org/content/11/483/eaau6267.full
Mar 13, 2019 · Technologies that enable extended drug release of medication have the potential to help patients adhere to long and frequent dosing regimens. For example, ingestible gastric resident devices for controlled release drug delivery of antimalarials and antiretrovirals have been demonstrated in large animal models (30, 31).Author: Malvika Verma, Karan Vishwanath, Feyisope Eweje, Feyisope Eweje, Niclas Roxhed, Niclas Roxhed, Tyler...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523542/
Apr 20, 2019 · However, oral drug delivery systems face challenges such as low bioavailability due to the heterogeneity of the gastrointestinal system, pH of the commensal flora, gastric retention time of the dosage form, surface area, and enzymatic activity . Conventional drug delivery systems may not overcome the issues imposed by the gastrointestinal tract ...Author: Julu Tripathi, Prakash Thapa, Ravi Maharjan, Seong Hoon Jeong
https://www.slideshare.net/akashaher07/1-gastroretentive-drug-delivery-systems
Jun 08, 2013 · 1 gastroretentive drug delivery systems 1. Presented By : Akash Aher(M.pharm -2nd semester)Guided by : Dr.G.S Asane(Dept. of pharmaceutics) 2. Contents Introduction Need of Gastric retention Advantages Limitation Physiology of Stomach Approaches of Gastric retention Evaluation of GRDDS Conclusion 3.
https://patents.google.com/patent/CN1520286B/en
The present invention provides a gastric retention controlled drug delivery system comprising: (a) a controlled release core comprising a drug, a highly swellable polymer and a gas generating agent, said core being capable of swelling and achieving floatation rapidly while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coat ...Author: 卡姆莱森·莫哈拉·德戴拉, 尼汀·柏拉查丹·戴蒙迪卡尔, 维沙里·维滋·戴维斯
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