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https://stm.sciencemag.org/content/4/122/122ra21.full
Feb 22, 2012 · Abstract. The first clinical trial of an implantable microchip-based drug delivery device is discussed. Human parathyroid hormone fragment (1–34) [hPTH(1–34)] was delivered from the device in vivo. hPTH(1–34) is the only approved anabolic osteoporosis treatment, but requires daily injections, making patient compliance an obstacle to effective treatment.Author: Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini, ...
https://www.ncbi.nlm.nih.gov/pubmed/22344516
Feb 22, 2012 · Furthermore, a net increase in bone mineral density requires intermittent or pulsatile hPTH(1-34) delivery, a challenge for implantable drug delivery products. The microchip-based devices, containing discrete doses of lyophilized hPTH(1-34), were implanted in eight osteoporotic postmenopausal women for 4 months and wirelessly programmed to ...Author: Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini, ...
http://news.mit.edu/2015/implantable-drug-delivery-microchip-device-0629
Jun 29, 2015 · An implantable, microchip-based device may soon replace the injections and pills now needed to treat chronic diseases: Earlier this month, MIT spinout Microchips Biotech partnered with a pharmaceutical giant to commercialize its wirelessly controlled, implantable, microchip-based devices that store and release drugs inside the body over many years.
https://health.howstuffworks.com/medicine/modern-technology/wireless-drug-delivery.htm
How Wireless Drug Delivery Works. by Marianne Spoon. NEXT PAGE . This microchip-based drug delivery device is programmable and can be wirelessly controlled to release each dose as specified.It's approximately 5 x 3 x 1 centimeters. Photo courtesy of MicroCHIPS Inc. Taking medicine daily may be the norm for people with chronic illnesses. ...
https://stm.sciencemag.org/content/scitransmed/4/122/122ra21.full.pdf
DRUG DELIVERY First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip Robert Farra,1* Norman F. Sheppard Jr.,1 Laura McCabe,1 Robert M. Neer,2 James M. Anderson,3 John T. Santini Jr.,4 Michael J. Cima,5 Robert Langer6 The first clinical trial of an implantable microchip-based drug delivery device is discussed.Author: Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini, ...
http://news.mit.edu/2012/wireless-drug-delivery-0216
Successful human tests for first wirelessly controlled drug-delivery chip. Clinical trial of the programmable, implantable device shows promise in treating osteoporosis. Anne Trafton, MIT News Office ... wirelessly controlled microchip that would deliver drugs after implantation in a patient’s body.
https://www.sciencedaily.com/releases/2012/02/120216144236.htm
Feb 16, 2012 · Massachusetts Institute of Technology. (2012, February 16). Successful human tests for first wirelessly controlled drug-delivery chip. ScienceDaily. Retrieved March 8, 2020 from www.sciencedaily ...
http://www.pharmtech.com/future-drug-delivery-wireless-microchip-based-drug-delivery
Aug 01, 2012 · The Future of Drug Delivery: Wireless Microchip-Based Drug Delivery A podcast with Robert Farra, president and COO of MicroCHIPS, who discusses wirelessly controlled and programmable microchip-based drug delivery as an alternative to subcutaneous injections.
https://medicalxpress.com/news/2012-02-successful-human-wirelessly-drug-delivery-chip.html
Successful human tests for first wirelessly controlled drug-delivery chip. by Anne Trafton, Massachusetts Institute of Technology
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