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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as tools to enable these strategies. These include benefits such as their small size which allows penetration of cell membranes,...Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Nanotechnology and Nanoparticles in Drug Delivery - Heart Disease: Researchers at North Carolina State University are developing a method to deliver cardiac stem cells to damaged heart tissue. They attach nanovesicles that are attracted to an injury to the stem cells to increase the amount of stem cells delivered to an injured tissue.
https://www.sciencedirect.com/science/article/pii/S1319016411000302
Nanoparticles (NP) are a type of colloidal drug delivery system comprising particles with a size range from 10 to 1000 nm in diameter. Nanoparticles may or may not exhibit size-related properties that differ significantly from those observed in fine particles or bulk materials ( Buzea et al., 2007 ).Author: Sagar R. Mudshinge, Amol B. Deore, Sachin Patil, Chetan M. Bhalgat
https://www.medscape.com/viewarticle/770397_5
Nov 01, 2019 · Challenges of Nanotechnology for Drug Delivery. Although progress in the application of nanotechnology to drug delivery has been dramatic and successful, as evidenced by some nanodrugs now on the market, several main challenges remain in this field (Figure 3).
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues. Thus, coating specific targeting ligand(s) on the surface of …Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.azonano.com/article.aspx?ArticleID=4668
Nov 01, 2017 · The application of nanotechnology for drug delivery provides the potential for enhanced treatments with targeted delivery and fewer side effects. Nanotechnology drug delivery applications occur through the use of designed nanomaterials as well as forming delivery systems from nanoscale molecules such as liposomes.Author: Azonano
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
A topical (used on the skin) antibacterial ointment for a localized infection or a cortisone injection of a painful joint can avoid some of the systemic side effects of these medications. There are other ways to achieve targeted drug delivery, but some medications can only be given systemically.
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