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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695828/
Oct 22, 2015 · 2. Transdermal Drug Delivery (TDD) TDD is a painless method of delivering drugs systemically by applying a drug formulation onto intact and healthy skin [2,5].The drug initially penetrates through the stratum corneum and then passes through the deeper epidermis and dermis without drug accumulation in the dermal layer.Author: Ahlam Zaid Alkilani, Maelíosa T.C. McCrudden, Ryan F. Donnelly
https://medical-dictionary.thefreedictionary.com/transdermal+drug+delivery
Transdermal drug delivery has some benefits: skipping first pass metabolism in liver, steady infusion of a drug over an extended period of time, better compliance of the patient due to ease of usage and reduced frequency of use, a choice for drugs with low therapeutic index and short half life, and so easy elimination of drug when toxicity occurs during the application [3,5,6].
https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
Transdermal Drug Delivery System. Transdermal therapeutic systems (TTS) were introduced as devices displaying the ability to release an active agent to the skin in a controlled manner, well below the maximum the tissue can accept. From: Strategies to Modify the …
https://academic.oup.com/bjaed/article/7/5/171/535087
Oct 01, 2007 · Transdermal delivery systems. There are two designs of transdermal patch currently available: the reservoir, or membrane-controlled system, and the matrix system. A reservoir patch holds the drug in a gel or solution and delivery is determined by a rate-controlling membrane between the drug reservoir and the skin (Fig. 3).Author: Lyn Margetts, Richard Sawyer
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/transdermal-delivery
Transdermal Delivery. Transdermal delivery is the term that is confined to a situation in which the drug diffuses through different layers of the skin into systemic circulation to elicit the therapeutic response (Brown et al., 2006).
https://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
ABSTRACT: A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. Often, this promotes healing to an injured area of the body. An advantage of a transdermal drug delivery route over other types of medication delivery such as oral, topical, intravenous, intramuscular, etc. is that the patch ...
https://www.researchgate.net/publication/261759007_TRANSDERMAL_DRUG_DELIVERY_SYSTEM_A_REVIEW
Transdermal drug delivery has made an important contribution to medical practice, but it has yet to fully achieve its potential as an alternative to the oral delivery and hypodermic injections.
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