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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://medical-dictionary.thefreedictionary.com/transdermal+drug+delivery
Transdermal drug delivery has some benefits: skipping first pass metabolism in liver, steady infusion of a drug over an extended period of time, better compliance of the patient due to ease of usage and reduced frequency of use, a choice for drugs with low therapeutic index and short half life, and so easy elimination of drug when toxicity occurs during the application [3,5,6].
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/transdermal-delivery
Transdermal delivery is the term that is confined to a situation in which the drug diffuses through different layers of the skin into systemic circulation to elicit the therapeutic response …
http://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
The main objective of transdermal drug delivery system is to deliver drugs into systemic circulation into the skin through skin at predetermined rate with minimal inter and intra patient variation. 3 Currently transdermal delivery is one of the most promising methods for drug application.
https://www.researchgate.net/publication/20025059_Transdermal_Delivery_Of_Drugs
Transdermal drug delivery systems, also known as ''patches,'' are dosage forms designed to deliver a therapeutically effective amount of drug across a patient's skin.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695828/
Oct 22, 2015 · 2. Transdermal Drug Delivery (TDD) TDD is a painless method of delivering drugs systemically by applying a drug formulation onto intact and healthy skin [2,5]. The drug initially penetrates through the stratum corneum and then passes through the deeper epidermis and dermis without drug accumulation in the dermal layer.Author: Ahlam Zaid Alkilani, Maelíosa T.C. McCrudden, Ryan F. Donnelly
https://deserthopetreatment.com/addiction-guide/administration-methods/transdermal/
Transdermal drug administration refers to substances that are absorbed through the skin. Some of the most common examples of these are nicotine patches or patches that contain painkillers, such as prescription opioids that release slowly over time in order to control chronic pain.
https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
Transdermal drug delivery systems facilitate the passage of therapeutic quantities of drug substances through the skin and into the general circulation for their systemic effects (Shaik et al., 2011). It has been found that drugs of herbal origin can be utilized with enhanced efficacy by incorporating them into transdermal drug patches.
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