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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/nasal/
About 3M Nasal Drug Delivery Technology Solutions Your patients deserve better nasal drug delivery than aqueous nasal sprays for allergic rhinitis. These sprays can drip down the throat and out of the nose, causing irritation, embarrassment, and unpleasant aftertastes. 3M can help deliver your treatments with intuitive patient-friendly nasal MDIs.
http://www.kurvetech.com/NasalTechnology.asp
Kurve Technology, Inc. designs and develops nasal drug delivery devices that offer pharmaceutical companies a palm-sized, cost-effective way to deliver drugs for both topical and systemic applications.
http://www.kurvetech.com/About.asp
Kurve Technology, Inc. designs and develops nasal drug delivery devices that offer pharmaceutical companies a palm-sized, cost-effective way to deliver drugs for both topical and systemic applications.
https://www.snbl-nds.com/technology/
SNBL has developed a proprietary nasal drug delivery technology, μco™ System, consisting of a powder carrier technology (μco™ Carrier) designed for increased drug absorption through its muco-adhesive properties and a delivery device technology designed for simple use, and complete and consistent delivery of intranasal powder formulations.
https://www.ondrugdelivery.com/wp-content/uploads/2018/11/Nov2005.pdf
There is a view that available nasal delivery technologies have not advanced in a meaningful way for perhaps more than a decade, meaning that a technology gap has opened up. The sector is waiting to take advantage of the opportunities the nasal route presents but cannot do so until a suitable nasal delivery technology becomes available.
http://intranasal.net/DeliveryTechniques/default.htm
Squeeze bottle delivery. Squeeze bottle delivery is another option for nasal drug delivery. However this technique is not able to deliver a measure dose of drug. Mucosal coverage is also dependent on the patient applying adequate pressure to the device to deliver the drug - so delivery is very variable.
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