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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/controlled-drug-release
In general, controlled release dosage forms are designed with the purpose of maintaining relatively steady concentrations of the drug in the blood, tissues, or target organs. Preferably, in this system the loading dose is released first, followed by the release of the maintenance dose of the drug …
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
Controlled release drug delivery employs drug-encapsulating devices from which therapeutic agents may be released at controlled rates for long periods of time, ranging from days to months. Such systems offer numerous advantages over traditional methods of drug delivery, including tailoring of drug release rates, protection of fragile
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://www.medindia.net/patients/patientinfo/drug-delivery-system.htm
drug delivery system or a controlled release technology. The technology uses binding chemicals that release drugs at a controlled rate at the targeted location in the body. are used to transport a drug to a specific part of the body. The concept of drug delivery is precisely integrated with the dosage of a drug and route of administration.
https://orbisbio.com/the-new-control-group-types-of-controlled-release-drugs/
“Controlled drug delivery is one which delivers the drug at a predetermined rate, for locally or systemically, for a specified period of time … Such systems offer numerous advantages over traditional methods of drug delivery, including tailoring of drug release rates, protection of fragile drugs and increased patient comfort and compliance.”
https://www.wisegeek.com/what-is-a-controlled-release-drug.htm
Oct 11, 2019 · A controlled release drug, which is also called a time release drug, is any type of pill that has been engineered to release the medication inside slowly rather than all at once. This technology has been available since the 1960s and makes it possible for patients to …
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