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https://www.sciencedirect.com/science/article/pii/S0168365901003303
Ushakov’s group synthesized numerous water soluble polymer–drug conjugates in the 1960s and 1970s . Mathé et al. pioneered conjugation of drugs to immunoglobulins, setting the stage for targeted delivery . Finally, Ringsdorf presented a clear concept of the use of polymers as targetable drug carriers in 1975 .Author: J Kopeček, P Kopečková, T Minko, Z.-R Lu, C.M Peterson
https://www.researchgate.net/publication/11852810_Water_soluble_polymers_in_tumor_targeted_delivery
The rationale for the use of water soluble polymers for anticancer drug delivery includes the potential to overcome some forms of anti-drug resistance and preferential accumulation in tumors due ...
https://www.ncbi.nlm.nih.gov/pubmed/16036307
Water-soluble polymers for targeted drug delivery to human squamous carcinoma of head and neck. Nan A(1), Ghandehari H, Hebert C, Siavash H, Nikitakis N, Reynolds M, Sauk JJ. Author information: (1)Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, 21201, USA.Author: Anjan Nan, Hamidreza Ghandehari, Carla Hebert, Hessam Siavash, Nikolaos Nikitakis, Mark Reynolds, Jo...
https://www.sciencedirect.com/science/article/pii/S0169409X04000468
Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. ... formation of PVP–lipid micelles expands the repertoire of micelles potentially useful as sustained release or targeted delivery systems for poorly water-soluble drugs.Author: Anatoly N. Lukyanov, Vladimir P. Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113619/
Apr 04, 2014 · Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10–100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation.Author: Yifei Zhang, Yixian Huang, Song Li
https://www.researchgate.net/publication/7709613_Water-soluble_polymers_for_targeted_drug_delivery_to_human_squamous_carcinoma_of_head_and_neck
Water-soluble polymers for targeted drug delivery to human squamous carcinoma of head and neck Article in Journal of Drug Targeting 13(3):189-97 · April 2005 with 16 Reads How we measure 'reads'
https://www.mdpi.com/2073-4360/3/4/1972/htm
Advances in polymer science have led to the development of novel drug delivery systems. Some polymers are obtained from natural resources and then chemically modified for various applications, while others are chemically synthesized and used. A large number of natural and synthetic polymers are available. In the present paper, only water soluble polymers are described. They have been explained ...Author: Veeran Gowda Kadajji, Guru V. Betageri
https://pubs.acs.org/doi/pdfplus/10.1021/acs.chemrev.5b00589
Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical ... in Tumor Therapy 5339 2. Principles of Tumor Targeting 5340 2.1. Passive Accumulation of Macromolecular ... Synthetic Water-Soluble Polymer−Drug Conju-gates for Cancer Therapy (Polymer Prodrugs) 5346
https://pubs.acs.org/doi/10.1021/bc034090j
Experiments and synthesis of bone-targeting epirubicin with the water-soluble macromolecular drug delivery systems of oxidized-dextran. Journal of Drug Targeting 2014 , 22 (4) , 343-351.Author: Dong Wang, Scott C Miller, Monika Sima, Pavla Kopečková, Jindrich Kopecek
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201900951
Sep 30, 2019 · Drugs can be noncovalently encapsulated in liposomes 7 and polymers 8 via hydrophobic interaction or covalently ... of hydrophobic antitumor drugs would be ideal for targeted delivery. Water‐soluble RNA nanoparticles have recently been developed for ... to solubilize hydrophobic CPT for targeted delivery in human tumor xenograft models. ...Author: Xijun Piao, Hongran Yin, Sijin Guo, Hongzhi Wang, Peixuan Guo
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