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https://pubmed.ncbi.nlm.nih.gov/17822972/
Intervention: After corneal specimens were obtained, the assigned study medication was instilled every hour, day and night, for 48 hours and on the third day, every hour by day and every 2 hours at night. For days 4 and 5, 1 drop every 2 hours by day and every 4 hours at night, and for days 6 …
https://www.visioninstitutecanada.com/storage/app/media/VIGAMOX-ALCON.pdf
administered 1 drop of VIGAMOX® solution to both eyes every 8 hours for a total of 10 doses. 3 Mean tear concentrations at 5 minutes following the first and last topical dose were 46.0 and 55.2:g/mL, respectively. Thereafter, they decline rapidly in a biphasic manner with the means
https://www.drugs.com/vigamox.html
severe burning, stinging, or irritation after using Vigamox eye drops; or. eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection). Common Vigamox side effects may include: fever, cough, sore throat or runny nose. This is not a complete list of side effects and others may occur.
https://www.reviewofoptometry.com/article/tackle-extreme-clinical-cases
Dr. Kabat administered a loading dose of Vigamox (i.e., two drops) to this patient and told her to administer one drop every hour while awake and one drop every three hours overnight. He saw her the next day and told her to continue using Vigamox hourly.
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