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https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021732s013lbl.pdf
Following subcutaneous insertion of one Vantas (histrelin implant) 50 mg implant in advanced prostate cancer patients (n = 17), peak serum concentrations of 1.10 ± 0.375 ng/mL (mean ± SD) occurred at a median of 12 hours. Continuous subcutaneous release was evident, as
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78b88748-8318-11dc-8314-0800200c9a66
Keep your arm clean and dry for 24 hours after VANTAS is placed. Avoid heavy lifting and exercise for 7 days with the arm that VANTAS was placed in. Avoid bumping the site for a few days. Your healthcare provider will give you complete instructions. After VANTAS is placed under the skin, the medicine is released into your body for 12 months.
https://www.rxlist.com/vantas-drug.htm
Following subcutaneous insertion of one VANTAS implant in advanced prostate cancer patients (n = 17), peak serum concentrations of 1.10 ± 0.375 ng/mL (mean ± SD) occurred at a median of 12 hours. Continuous subcutaneous release was evident, as serum levels were sustained throughout the 52 week dosing period (see Figure 1).
https://www.drugs.com/vantas.html
The Vantas implant is used to treat symptoms of prostate cancer in men. Vantas treats only the symptoms of prostate cancer but does not treat the cancer itself. Warnings. Vantas can cause side effects such as crying spells, anger, aggression, and feeling restless or irritable. Call your doctor if you have any new or worsening mental problems.
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