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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689521/
Jan 19, 2017 · Despite many attempts, only a few liposomal and protein‐based NPs have been approved for cancer drug delivery, including Doxil and Abraxane—and these are all passive‐targeting delivery agents relying on the enhanced permeability and retention (EPR) effect for tumor localization. 5, 10, 11 Liposomal NPs are limited by particle instability, rapid clearance, and spontaneous membrane fusion …Author: Marcus J. Rohovie, Maya Nagasawa, James R. Swartz
https://indianexpress.com/article/technology/science/creating-virus-like-particles-for-drug-delivery/
Feb 06, 2016 · Creating virus-like particles for drug delivery Cells are generally impregnable to most macromolecules. It is this ability to penetrate cells that makes some viruses potentially useful carriers of …Works For: The Indian Express
https://www.nature.com/articles/s41598-019-40388-x
Mar 08, 2019 · However, up until now, no information is available on the development of a thermally-responsive drug delivery system based on a virus-like particle (VLP). VLP is a protein shell of a virus …Author: Qiu Xian Thong, Roya Biabanikhankahdani, Roya Biabanikhankahdani, Kok Lian Ho, Noorjahan Banu Alithe...
https://www.ncbi.nlm.nih.gov/pubmed/27474402
Virus-like particles as drug delivery vectors. Zdanowicz M(1), Chroboczek J(2). Author information: (1)Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.Author: Michał Zdanowicz, Jadwiga Chroboczek
https://aiche.onlinelibrary.wiley.com/doi/full/10.1002/btm2.10049
Abstract. Most drug therapies distribute the agents throughout the entire body, even though the drugs are typically only needed at specific tissues. This often limits dosage and causes discomfort and harmful side‐effects. Significant research has examined nanoparticles (NPs) for use as targeted delivery vehicles for therapeutic cargo, however,...Author: Marcus J. Rohovie, Maya Nagasawa, James R. Swartz
https://www.sciencedirect.com/science/article/pii/S0169409X12000087
Virus-like particles (VLPs) based on biological building blocks have become an emerging type of nanocarriers for targeted drug delivery. Viruses have the unique advantage of structural uniformity and their chemical and conformational structures can be produced precisely and in large quantities.Author: Y. Ma, Y. Ma, R.J.M. Nolte, Jeroen Johannes Lambertus Maria Cornelissen
https://aiche.onlinelibrary.wiley.com/doi/pdf/10.1002/btm2.10049
neering of viral capsids as noninfectious protein-based NPs—termed virus-like particles (VLPs). This review covers the research that has been performed thus far and outlines the potential for these VLPs to become highly effective delivery vehicles that overcome the many challenges encountered for targeted delivery of therapeutic cargo.Author: Marcus J. Rohovie, Maya Nagasawa, James R. Swartz
https://www.sciencedirect.com/topics/immunology-and-microbiology/virus-like-particle
Virus-like particles (VLPs) are self-assembled nanoparticles that have a regular, symmetrical structure. They have been utilized for drug delivery and targeting, imaging, and antigen display.
https://www.slideshare.net/MohammadAbrarGayath/virus-like-particles
Jan 16, 2017 · Therefore, SUVs are considered safer than full pathogen-based inactivated or live attenuated vaccines Virus-like particles (VLPs) represent a major advancement in the development of SUVs with enhanced immunogenicity. TYPES Non-enveloped VLPs are typically composed of one or more components...
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