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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · There are different viral and nonviral vectors for gene delivery, but all gene therapy applications depend on the fact that the genetic material needs to be delivered across the cell membrane and ultimately to the cell nucleus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356701/
Jan 04, 2019 · Due to high transduction efficiency and minimal human symptoms, numerous efforts have been made to optimize the AdV as a gene delivery vector. First generation recombinant AdV vectors are devoid of viral gene E1 . These vectors cause an acute as well as chronic immune response.Author: Christine L. Xu, Merry Z. C. Ruan, Vinit B. Mahajan, Stephen H. Tsang
https://seekingalpha.com/article/4305556-gene-therapy-series-2-delivery-systems-in-gene-therapy-including-viral-vectors
Nov 11, 2019 · Continuing with the series of articles on gene therapy, this article will discuss the various delivery methods for gene therapies with a focus on viral vectors.The article also discusses the classific
https://www.takarabio.com/learning-centers/gene-function/viral-transduction/recombinant-virus-comparison
Viral gene delivery allows the introduction and expression of a gene of interest in almost any mammalian cell type. However, selecting the best viral gene delivery system for …
https://www.thermofisher.com/us/en/home/references/gibco-cell-culture-basics/transfection-basics/gene-delivery-technologies.html
Viral delivery: Highest efficiency amongst gene delivery methods (80–90% transduction efficiency in primary cells) Works well with difficult to transfect cell types; Can be used for in vivo delivery of nucleic acids; Can be used for making stable cell lines (retroviral …
https://www.researchgate.net/publication/233841223_Viral_and_nonviral_delivery_systems_for_gene_delivery
Although numerous viral and nonviral gene delivery systems have been developed in the last 3 decades, no delivery system has been designed that can be applied in gene therapy of all kinds of cell ...
https://www.businesswire.com/news/home/20191007005150/en/Genprex%E2%80%99s-Pioneering-Non-Viral-Delivery-Gene-Therapy-Gaining
“Most gene therapy research has been focused on using viral delivery systems to deliver genes to cancer cells, and today most approved gene therapies for non-blood cell therapies use a viral ...
http://juventasinc.com/non-viral-gene-therapy.html
Gene therapy generally refers to the delivery of DNA into a patient’s cells to treat a target disease. The two major classes of gene therapy are viral, which uses recombinant viruses to promote long-term or permanent genomic modification, and non-viral, which uses a naked DNA plasmid to promote short-term therapeutic protein expression locally at the site of drug administration.
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