Vector-Mediated Drug Delivery To The Brain

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Vector-mediated drug delivery to the brain.

    https://www.ncbi.nlm.nih.gov/pubmed/11728213
    The current challenge is to develop drug-delivery strategies that will allow the passage of therapeutic drugs through the BBB in a safe and effective manner. This review focuses specifically on the strategies developed to enhance drug delivery across the BBB with an emphasis on the vector-mediated strategy. PMID: 11728213 [Indexed for MEDLINE]Author: Jamal Temsamani, Christophe Rousselle, Anthony R Rees, Jean-Michel Scherrmann

Vector-mediated drug delivery to the brain Request PDF

    https://www.researchgate.net/publication/11628103_Vector-mediated_drug_delivery_to_the_brain
    Vector-mediated drug delivery to the brain. ... review focuses specifically on the strategies developed to enhance drug delivery across the BBB with an emphasis on the vector-mediated strategy.

Vector-mediated drug delivery to the brain - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0169409X98000878
    Vector-mediated drug delivery to the brain employs the chimeric peptide technology, wherein a non-transportable drug is conjugated to a blood–brain barrier (BBB) transport vector. The latter is a modified protein or receptor-specific monoclonal antibody that undergoes receptor-mediated transcytosis through …Author: William M. Pardridge

(PDF) Vector-mediated drug delivery to the brain

    https://www.researchgate.net/publication/222976387_Vector-mediated_drug_delivery_to_the_brain
    Vector-mediated drug delivery to the brain employs the chimeric peptide technology, wherein a non-transportable drug is conjugated to a blood–brain barrier (BBB) transport vector.

Vector-mediated peptide drug delivery to the brain ...

    https://www.sciencedirect.com/science/article/pii/0169409X9500007T
    Ongoing brain vector discovery programs may lead to new vectors with higher degrees of activity and brain specificity. The chimeric peptide approach to brain drug delivery is an advanced technology that requires integrated progress in three inter-dependent spheres: the vector sphere, the linker sphere, and the drug activity sphere.Author: William M. Pardridge

Vector-mediated drug delivery to the brain: Expert Opinion ...

    https://www.tandfonline.com/doi/abs/10.1517/14712598.1.5.773
    Feb 23, 2005 · As a consequence of the growing ageing population, many neurodegenerative diseases, cancer and infections of the brain will become more prevalent. Despite major advances in neuroscience, many potential therapeutic agents are denied access to the central nervous system (CNS) because of the existence of the blood-brain barrier (BBB). This barrier is formed by the endothelial cells of the brain ...Author: Jamal Temsamani, Christophe Rousselle, Anthony R Rees, Jean-Michel Scherrmann

Brain specific delivery - LinkedIn SlideShare

    https://www.slideshare.net/sayedasalma/brain-specific-delivery
    Jul 24, 2018 · • Drug delivery to the brain is the process of passing therapeutically active molecules across the Blood Brain Barrier for the purpose of treating brain maladies. • This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the Blood Brain Barrier.

Pharmacologic effects in vivo in brain by vector-mediated ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC46146/
    Apr 01, 1993 · Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery. U Bickel , T Yoshikawa , E M Landaw , K F Faull , and W M Pardridge Department of Medicine, University of California School of Medicine, Los Angeles 90024.Author: U Bickel, T Yoshikawa, E M Landaw, K F Faull, W M Pardridge

Vector-mediated drug delivery to the brain, Advanced Drug ...

    https://www.deepdyve.com/lp/elsevier/vector-mediated-drug-delivery-to-the-brain-Jm8i0S29Cu
    Vector-mediated drug delivery to the brain employs the chimeric peptide technology, wherein a non-transportable drug is conjugated to a blood–brain barrier (BBB) transport vector. The latter is a modified protein or receptor-specific monoclonal antibody that undergoes receptor-mediated transcytosis through …

Vector-mediated drug delivery to the brain. - Abstract ...

    http://europepmc.org/abstract/MED/11728213
    Oct 01, 2001 · The current challenge is to develop drug-delivery strategies that will allow the passage of therapeutic drugs through the BBB in a safe and effective manner. This review focuses specifically on the strategies developed to enhance drug delivery across the …Author: Jamal Temsamani, Christophe Rousselle, Anthony R Rees, Jean-Michel Scherrmann

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