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https://www.researchgate.net/publication/7143935_Evaluation_of_a_vaporizing_device_VolcanoR_for_the_pulmonary_delivery_of_tetrahydrocannabinol
Evaluation of a vaporizing device (Volcano®) for the pulmonary delivery of tetrahydrocannabinol Article (PDF Available) in Journal of Pharmaceutical Sciences 95(6):1308-17 · June 2006 with 3,560 ...
https://www.sciencedirect.com/science/article/pii/S0378517310001912
Local delivery of medication to the lungs is highly desirable, especially in patients with specific pulmonary diseases such as cystic fibrosis, asthma, chronic pulmonary infections or lung cancer. The principal advantages include reduced systemic side effects and higher doses of the applicable medication at the site of drug action.
http://rc.rcjournal.com/content/61/8/1122
E-cigarettes are a diverse set of devices that are designed for pulmonary delivery of nicotine through an aerosol, usually consisting of propylene glycol, nicotine, and flavorings. The devices heat the nicotine solution using a battery-powered circuit and deliver the resulting vapor into the proximal airways and lung. Although the current devices on the market appear to be safer than smoking ...
https://www.cdc.gov/tobacco/basic_information/e-cigarettes/index.htm
Get the facts about electronic cigarettes, their health effects and the risks of using e-cigarettes. E-cigarettes are sometimes called “e-cigs,” “vapes,” “e-hookahs,” “vape pens,” and “electronic nicotine delivery systems (ENDS).”
https://pulmccm.org/review-articles/vaping-associated-lung-injury-part-2/
Jon-Emile S. Kenny MD [@heart_lung] “There are sadistic scientists who hurry to hunt down errors instead of establishing the truth."-Marie Curie. In part 1 of Vaping-Associated Lung Injury, the very basics of electronic nicotine delivery systems [ENDS] were covered as well as highlights on clinical presentation, radiology and pathology. In this second part, flurries of toxic mechanisms are ...
https://en.wikipedia.org/wiki/Alcohol_inhalation
Alcohol inhalation is a method of administering alcohol (also known as ethanol) directly into the respiratory system, with aid of a vaporizing or nebulizing device. It is chiefly applied for recreational use, when it is also referred to as alcohol smoking, but it has medical applications for testing on laboratory rats and treatment of pulmonary edema in humans.
https://journals.physiology.org/doi/full/10.1152/ajplung.00389.2017
Electronic cigarettes (e-cigs) are advertised as a less harmful nicotine delivery system or as a new smoking cessation tool. We aimed to assess the in vivo effects of e-cig vapor in the lung and to compare them to those of cigarette smoke (CS).
https://preventionforme.org/wp-content/uploads/ENDStoolkit.Final_.pdf
ENDS aerosol is NOT harmless water vapor. • Some aerosols contain propylene glycol which can cause respiratory irritation and bronchial constriction. 1. This is a concern for people with chronic obstructive pulmonary disease or asthma. • ENDS aerosol can pose a risk for decreased lung development, breathing difficulties, lower
https://journal.chestnet.org/article/S0012-3692(12)60327-4/fulltext
Debate exists over the scientific evidence for claims that electronic cigarettes (e-cigarettes) have no health-related ramifications. This study aimed to assess whether using an e-cigarette for 5 min has an impact on the pulmonary function tests and fraction of exhaled nitric oxide (Feno) of …
https://doi.apa.org/getdoi.cfm?doi=10.1037/a0020834
Pulmonary function showed no adverse changes. These results demonstrate that NP inhalations produce rapid increases in plasma nicotine concentrations, provide satisfaction and are well tolerated. At the 20 μg/puff dose, peak nicotine concentrations were higher than with the Nicotrol/Nicorette nicotine vapor inhaler cartridge.
https://www.sbir.gov/sbirsearch/detail/820213
Jul 24, 2015 · The delivery device could be in the form of a vaporizer, nebulizer, dry-powder inhaler or any other FDA-approvable pulmonary delivery device. Phase 1 of the project characterizes the quantity and reproducibility of CBD delivered in a single 5-second puff, as well as the identities and the amounts of all other agents in the vapor/aerosol.
https://quizlet.com/108847116/respiratory-flash-cards/
significantly increase the oxygen delivery to tissues. What type of nerve fibers are stimulated by capsaicin that causes apnea, then rapid, shallow breathing? ... less O2 is provided to those tissues. F. The presence of water vapor in the air will reduce the partial pressure of oxygen. T. ... Pulmonary circulation is a ____ resistance and ...
https://www.sciencedirect.com/book/9780128144879/drug-delivery-systems
The high permeability and surface area of lung provide an alternative route for drug delivery in ailments such as asthma, chronic obstructive pulmonary disease, and diabetes. In the pulmonary route the successful administration of drugs needs a proper balance between drug formulation, the inhalation device, and the patients.
https://www.aarc.org/wp-content/uploads/2018/03/aersol-guides-for-hcp.pdf
Pulmonary Disease Aerosol Delivery Devices, 3rd Edition To ensure effective drug delivery to the airways with a DPI, patients must be able to generate a minimum peak inspi-ratory flow rate of 30 L/min. For best drug delivery, achiev-ing inspiratory flow rates of 60-90 L/min provides superior efficacy in delivery.
https://www.jci.org/articles/view/131336
Differences in exposure delivery systems and vapor used (variable addition of nicotine or flavorings) may explain the contrasting findings observed in some of these studies, although they uniformly demonstrate that ENDS exposure affects several aspects of pulmonary immune homeostasis.
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