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https://www.researchgate.net/publication/326535280_Formulation_and_Evaluation_of_Valsartan_Pulsincap_Drug_Delivery_System_for_Treatment_of_Hypertension
Formulation and Evaluation of Valsartan Pulsincap Drug Delivery System for Treatment of Hypertension Article (PDF Available) · January 2018 with 131 Reads How we measure 'reads'
https://www.researchgate.net/publication/263169702_Formulation_And_Evaluation_Of_Valsartan_Pulsatile_Drug_Delivery_Systems
Aim: Preparation and evaluation of oral pulsatile drug delivery (PDD) systems to deliver valsartan at the early morning meeting the expected hypertension surge according to the circadian rhythm of ...
http://europepmc.org/patents/PAT/WO2008064338
The present invention relates to the method of increasing the bioavailability of Angiotensin II Receptor Blockers by preparing a composition of an ARB that is capable of releasing the medicament intermittently in the GI tract in pulses at predetermined time intervals. In one aspect, the present invention relates to orally deliverable compositions designed to release solubilized ARB, in ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649783/
Design of Chronomodulated Drug Delivery System of Valsartan: ... The aim of the present study was to design and evaluate a chronomodulated time-clock pulsatile tablets of valsartan to release it after a certain lag time, independent of the gastrointestinal pH, in its absorption window to cope with the circadian rhythm of human body for blood ...
https://www.sciencedirect.com/science/article/pii/S1818087613000342
Pulsatile core-in-cup valsartan tablet formulations: In vitro evaluation. ... Pulsatile drug delivery system (PDDS) ... The angle of repose of valsartan and the core formulation mixture was determined by the fixed funnel method . The bulk density ...Author: M.S. Sokar, A.S. Hanafy, A.H. El-Kamel, S.S. El-Gamal
http://ajptonline.com/HTMLPaper.aspx?Journal=Asian%20Journal%20of%20Pharmacy%20and%20Technology;PID=2018-8-2-1
The aim of the present study was to develop and evaluate pulsatile drug delivery system of Valsartan for the treatment of hypertension. It is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack. ... Formulation of pulsatile (modified pulsincap) drug ...Author: Mangesh A. Bhutkar, Somnath D. Bhinge
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465146/
The formulation containing sodium alginate 5.2% and potassium bicarbonate 0.625% was in the optimum zone and has the potential for time-controlled pulsatile delivery of Valsartan. The optimized formulation exhibited release profiles that were close to the predicted responses.
http://ijpar.com/sites/default/files/articles/IJPAR_14_930%2041-47.pdf
The aim of present study is to formulation and evaluation of Valsartan pulsincap for pulsatile drug delivery system . Valsartan pulsincap will be prepared to release the drug after predetermined lag period, to meet the therapeutic requirement of the body. METHODOLOGY PREPARATION OF THE STANDARD CALIBRATION CURVES OF VALSARTAN
https://www.tandfonline.com/doi/abs/10.3109/03639045.2015.1014374
The present work is aimed to develop and optimize pulsatile delivery during dissolution of an improved formulation of valsartan to coordinate the drug release with circadian rhythm. Preliminary studies suggested that β cyclodextrin could improve the solubility of valsartan and showed A L type solubility curve. A 1:1 stoichiometric ratio of ...Author: Sunny Shah, Romik Patel, Moinuddin Soniwala, Jayant Chavda
http://www.rroij.com/open-access/design-and-characterization-of-valsartan-loaded-presscoated-pulsatile-tablets-.php?aid=85641
Design and Characterization of Valsartan Loaded Press Coated Pulsatile Tablets. ValsartanSowjanya Battu *, Madhavi K, Bhikshapathi DBRN, and Abbulu K. Department of Pharmaceutics, CMR College of Pharmacy, Telangana, IndiaAuthor: Sowjanya Battu, Madhavi K, Bhikshapathi Dbrn, Abbulu K
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