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https://www.sciencedaily.com/releases/2010/07/100718204733.htm
Jul 19, 2010 · Georgia Institute of Technology Research News. (2010, July 19). Vaccine-delivery patch with dissolving microneedles eliminates 'sharps,' boosts protection. ScienceDaily. Retrieved January 8, …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917494/
Although this study did not assess dose-sparing, the most significant immunologic difference between vaccine delivery using dissolving microneedles versus IM immunization is the 1000-fold more efficient lung virus clearance after microneedle vaccination, which is …Author: Sean P Sullivan, Dimitrios G Koutsonanos, Maria del Pilar Martin, Jeong Woo Lee, Vladimir Zarnitsyn,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771849/
Sep 04, 2013 · Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods.Author: Xiaoyun Hong, Liangming Wei, Fei Wu, Zaozhan Wu, Lizhu Chen, Zhenguo Liu, Weien Yuan
https://www.news.gatech.edu/2010/07/18/vaccine-delivery-patch-dissolving-microneedles-boosts-protection
Jul 18, 2010 · Before dissolving microneedles can be made widely available, however, clinical studies will have to be done to assure safety and effectiveness. Other vaccine formulation techniques may also be studied, and researchers will want to better understand why vaccine delivery with dissolving microneedles has been shown to provide better protection.
https://www.dovepress.com/technology-update-dissolvable-microneedle-patches-for-vaccine-delivery-peer-reviewed-fulltext-article-MDER
Dissolvable microarray patches or dissolving microneedles (DMN) have been proposed as an innovative vaccine delivery platform that could potentially revolutionize vaccine delivery and circumvent many of the challenges faced with current vaccine strategies.Author: Aoife M Rodgers, Ana Sara Cordeiro, Ryan F Donnelly
https://www.researchgate.net/publication/259743922_Microneedle_Patches_for_Vaccine_Delivery
Microneedle Patches for Vaccine Delivery. ... dissolving microneedles consistin g of thermoplastic starch ... After a patch is applied to the skin, vaccine diffuses into the dermis and epidermis ...
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