We have collected information about Using Drug Excipient Interactions For Sirna Delivery for you. Follow the links to find out details on Using Drug Excipient Interactions For Sirna Delivery.
https://www.sciencedirect.com/science/article/pii/S0169409X11002341
SiRNA is the trigger of RNA interference, a mechanism discovered in the late 1990s. To release the therapeutic potential of this versatile but large and fragile molecule, excipients are used which either interact by electrostatic interaction, passively encapsulate siRNA or are covalently attached to enable specific and safe delivery of the drug substance.Author: Katharina Bruno
https://www.ncbi.nlm.nih.gov/pubmed/21945846
Using drug-excipient interactions for siRNA delivery. Bruno K(1). Author information: (1)Novartis Pharma AG, Technical Research & Development (TRD), Pharmaceutical and Analytical Development (PHAD), CH-4057 Basel, Switzerland. [email protected] SiRNA is the trigger of RNA interference, a mechanism discovered in the late 1990s.Author: Katharina Bruno
https://www.researchgate.net/publication/51672933_Using_drug-excipient_interactions_for_siRNA_delivery
Using drug-excipient interactions for siRNA delivery Article · Literature Review in Advanced drug delivery reviews 63(13):1210-26 · September 2011 with 29 Reads How we measure 'reads'
https://www.deepdyve.com/lp/elsevier/using-drug-excipient-interactions-for-sirna-delivery-Sy1P0dhg8Z
Oct 01, 2011 · Using drug-excipient interactions for siRNA delivery Using drug-excipient interactions for siRNA delivery Bruno, Katharina 2011-10-01 00:00:00 SiRNA is the trigger of RNA interference, a mechanism discovered in the late 1990s. To release the therapeutic potential of this versatile but large and fragile molecule, excipients are used which either interact by electrostatic interaction, passively ...
https://www.sciencedirect.com/science/article/pii/S1818087614000646
The attitude of big pharmaceutical companies to RNAi drugs has also become over-optimistic. In summary, a good delivery system is the key to siRNA drug development. Once research into siRNA drug delivery systems makes a significant breakthrough, siRNA will occupy a strong position in the drug market, especially the anti-cancer drug market.Author: Cong-fei Xu, Jun Wang
https://www.researchgate.net/publication/326658505_Drug-Excipient_Interaction_and_Incompatibilities
drug excipient interactions are hydrolysis, oxidation, isomerization, photolysis, and poly- ... delivery system (SMEDDS), self-emulsifying drug delivery syst ems, solid lipid nano-
https://us.bioneer.com/SAMiRNA/siRNADrugdevelopmentProgram.aspx
Bioneer's siRNA Drug Development Program using SAMiRNA Technology. Vertically integrated processes within Bioneer's siRNA Drug Development Program provide a total solution for siRNA therapeutics discovery and development, from siRNA design/synthesis and preclinical tests to IND filing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929451/
Polysaccharide Nanoparticles for Efficient siRNA Targeting in Cancer Cells by Supramolecular pK a Shift. ... Polysaccharide Nanoparticles for Efficient siRNA Targeting in Cancer Cells by Supramolecular pK a Shift. Sci. ... Using drug-excipient interactions for siRNA delivery. Adv. Drug. Delivery Rev. 63, 1210–1226 (2011).Author: Ying-Ming Zhang, Yang Yang, Yang Yang, Yu-Hui Zhang, Yu Liu
https://www.europeanpharmaceuticalreview.com/article/13688/ten-years-of-sirna-a-clinical-overview/
Jul 10, 2012 · In 2001, small interfering RNA (siRNA) was discovered as the mediator of RNA interference (RNAi), a transient and specific repression mechanism of protein expression1. After the pharmaceutical industry became aware of the intrinsic versatility and potential of this molecule, a race to develop the first siRNA based drug began. However, the initial hype was followed by the realisation …
https://pubs.acs.org/doi/abs/10.1021/bi048950a
Enhanced survivin siRNA delivery using cationic liposome incorporating fatty acid-modified polyethylenimine. ... Using drug-excipient interactions for siRNA delivery. Advanced Drug Delivery Reviews 2011, 63 (13) , 1210-1226. DOI: 10.1016/j.addr.2011.09.003.Author: Sebastien Spagnou, Andrew D. Miller, Michael Keller
Searching for Using Drug Excipient Interactions For Sirna Delivery?
You can just click the links above. The data is collected for you.
