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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · PAMAM dendrimers are one of the most used dendrimers for drug delivery systems [5,6,7]. The dendrimer architecture has three main sites for drug entrapment by using various mechanisms: (i) void spaces (by molecular entrapment); (ii) branching points (by hydrogen bonding); and (iii) outside surface groups by (charge–charge interactions) ( Figure 1 ).Author: Abhay Singh Chauhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Dendrimers are the emerging polymeric architectures that are known for their defined structures, versatility in drug delivery and high functionality whose properties resemble with biomolecules.
https://www.hindawi.com/journals/jnm/2014/507273/
N. A. Peppas, “Star polymers and dendrimers: prospects of their use in drug delivery and pharmaceutical applications,” Controlled Release Society Newsletter, vol. …Author: B. Noriega-Luna, Luis A. Godínez, Francisco J. Rodríguez, A. Rodríguez, G. Zaldívar-Lelo de Larrea, ...
https://www.pharmatutor.org/articles/dendrimers-novel-drug-delivery-overview
Dendrimers are being used as drug delivery systems for various drugs like anticancer drugs (methotrexate), drug for prevention of HIV, enhancing bioavailability of pilocarpine for ocular drug delivery. Dendrimers help in achieving increased bioavailability, sustained, controlled as well as targeted release of drug.
https://www.worldofchemicals.com/19/chemistry-articles/dendrimers-for-drug-delivery.html
Dendrimers are considered as the Polymers of 21 st century. The discovery and creation of new drugs is timely and costly process. It is estimated that every new drug takes 12 to 15 years to develop, at a cost of over $800 million.
http://www.pharmtech.com/role-dendrimers-topical-drug-delivery
Nov 02, 2008 · In particular, dendrimers have been used as carriers for drug delivery by various routes of administration, including parenteral, oral, topical, transdermal, and ocular. Although widely researched for more than two decades, only one clinical study is underway using dendrimers as microbicides (43).
https://pubs.acs.org/doi/10.1021/mp050023q
Jun 22, 2005 · Starpharma focuses on the use of dendrimers as drugs in their own right, in contrast to dendrimers as drug delivery vehicles or diagnostics. This contextual review describes how dendrimers offer a unique platform for exploring chemical diversity on the nanoscale and how the production of dendrimer libraries covering a diverse array of macromolecular structures can be used in drug discovery …Author: Tom D. McCarthy, Peter Karellas, Scott A. Henderson, Michael Giannis, David F. O'Keefe, Graham Heery...
https://www.slideshare.net/AnilPethe/dendrimers-in-drug-delivery-107157133
Jul 23, 2018 · The drug loading can be tuned by varying the generation number of the dendrimer Release of the drug can be controlled by incorporating degradable linkages between the drug and dendrimer Conjugates of PAMAM dendrimers with cisplatin, a potent anticancer drug with non-specific toxicity and poor water solubility. The conjugates show increased solubility, decreased systemic toxicity and …
https://www.sciencedirect.com/science/article/pii/S0079670013000853
Peptide dendrimers have been used in industry as surfactants, and in biomedical field as multiple antigen peptides (MAP) [77], protein mimics [78] and vehicles for drug and gene delivery [77], [78]. Additionally, Darbre and Reymond have utilized peptide dendrimers as esterase catalysts [79].Author: Prashant Kesharwani, Keerti Jain, Narendra Kumar Jain
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