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https://www.sciencedirect.com/science/article/pii/S0169131706001505
Use of clays as drug delivery systems: Possibilities and limitations 1. Introduction. The main concept in modified delivery technology is that any pharmaceutical dosage... 2. Modified Drug Delivery Systems (MDDS) MDDS cover a wide range of products,... 3. Use of clay minerals to improve drug ...Author: C. Aguzzi, P. Cerezo, C. Viseras, C. Caramella
https://www.researchgate.net/publication/222027101_Use_of_Clays_as_Drug_Delivery_Systems_Possibilities_and_Limitations
The need for safe, therapeutically effective and patient-compliant drug delivery systems continuously leads researchers to design novel tools and strategies. Clay minerals are widely used materials in drug products both as excipients and active agents.
https://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra03942a
Clays belong to a category of silica layered ingredients that are commonly used in the pharmaceutical industry, either as ingredients or in combination in composites and hybrids. The specific structure of clay provides effective drug delivery systems with the ability to interact with drugs and to control release.Author: Maryam Jafarbeglou, Majid Abdouss, Ahmad Mousavi Shoushtari, Majid Jafarbeglou
https://www.future-science.com/doi/abs/10.4155/tde-2017-0041
Clays for drug delivery have been used from ancient time due to the large availability of clay minerals and their unprecedented properties. The empirical use of nanoclays from the past is converted in a stimulating scientific task aimed at building up nanoarchitectonic vehicles for drug delivery in a targeted and stimuli-responsive fashion.Author: Giuseppe Lazzara, Serena Riela, Rawil F Fakhrullin
https://biomedres.us/pdfs/BJSTR.MS.ID.002677.pdf
drug delivery systems [4] made use of acid activation to treat natural montmorillonite [34] used two distinct steps to synthesize a polymer / clay hybrid material; in the first step modification ofAuthor: FabrÃcia de Castro Silva, Luciano Clécio Brandão Lima, Luzia Maria Castro Honório, Pollyana Trig...
https://www.sciencedirect.com/science/article/pii/S0169131710000219
Besides these classic pharmaceutical uses, clay minerals may be effectively used in the development of new drug delivery systems (DDS). Strictly speaking, all pharmaceutical dosage forms are DDS, as they are used to administer drugs meant to reach the site of action and maintain a certain concentration during treatment.Author: C. Viseras, C. Viseras, P. Cerezo, R. Sanchez, I. Salcedo, C. Aguzzi
https://www.researchgate.net/publication/248536777_Current_challenges_in_clay_minerals_for_drug_delivery
This study reviews current challenges of clay minerals for drug delivery. Clay minerals are widely used in conventional pharmaceutical dosage forms both as excipients and active agents. Clay minerals may interact with drug molecules, but also with inactive components of medicinal products such as polymers.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725630/
Methotrexate (MTX), an anticancer agent, was successfully intercalated into the anionic clay, layered double hydroxides to form a new nanohybrid drug.Author: Goeun Choi, Huiyan Piao, Zeid A Alothman, Ajayan Vinu, Chae-Ok Yun, Jin-Ho Choy
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