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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
1. Mechanisms of Ultrasonic-Enhanced Drug Delivery. Ultrasound (US) has been employed to enhance the delivery and activity of drugs for the past two decades. In the past 6 years, however, research in US-activated drug delivery has blossomed with the introduction of gas bubbles.Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
https://en.wikipedia.org/wiki/Ultrasonic_drug_delivery
Sonodynamic therapy is a proposed form of treatment using drugs that only become cytotoxic upon exposure to ultrasound. Since ultrasound can be focused into small tissue volumes within the body, this method provides a potential means of localizing treatment and reducing the risk of toxic side-effects elsewhere in the body.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30332-2/fulltext
Aug 01, 2018 · The combined treatment of LTLD and non-invasive focused ultrasound hyperthermia in this study seemed to be clinically feasible, safe, and able to enhance intratumoural drug delivery, providing targeted chemo-ablative response in human liver tumours that were refractory to …Author: Paul C Lyon, Paul C Lyon, Paul C Lyon, Michael D Gray, Christophoros Mannaris, Lisa K Folkes, Michae...
https://www.tandfonline.com/doi/abs/10.1517/17425247.1.1.37
Apr 27, 2018 · Ultrasonic-enhanced gene delivery has been studied in various tissues, including cardiac, vascular, skeletal muscle, tumour and even fetal tissue. Ultrasonic-assisted delivery of proteins has found most application in transdermal transport of insulin.Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
https://www.researchgate.net/publication/7471344_Ultrasonic_Drug_Delivery_-_A_General_Review
effective drug delivery vehicles, being both the carrier and the activator for the ultrasonic drug delivery. Some drugs can spontaneously associate with the surface of liposomes and microbubbles.
http://tcr.amegroups.com/article/view/3354/html
Review of ultrasound mediated drug delivery for cancer treatment: updates from pre-clinical studies Therapeutic ultrasound has been used to thermally ablate solid tumors since the 90s, and a variety of cancers are presently being treated clinically, taking advantage of ultrasound- or …
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