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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406285/
Localization, structural elucidation, molecular and functional characterization of these membrane transport systems may aid in better design of targeted drug delivery systems. This review highlights sodium dependent multivitamin transporter (SMVT) as a highly promising target for drug delivery.Author: Aswani Dutt Vadlapudi, Ramya Krishna Vadlapatla, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361857/
Oct 24, 2018 · Transporter-targeted nanoparticulate drug delivery systems (nano-DDS) have emerged as promising nanoplatforms for efficient drug delivery. Recently, great progress in transporter-targeted strategies has been made, especially with the rapid developments in nanotherapeutics.Author: Hongyan Su, Yan Wang, Shuo Liu, Yue Wang, Qian Liu, Guangxuan Liu, Qin Chen
https://pharmacy.vcu.edu/pharmaceutics/research/drug-transporters/
Additionally, transporters can work together with drug metabolizing enzymes to eliminate drugs from the body. Research on drug transporters involves many disciplines of science and offers many possibilities for scientific investigations. Organic Solute Carriers (SLC22 transporter family)
https://www.sciencedirect.com/science/article/pii/B978190756886250006X
Transporter-targeted drug delivery to the posterior segment The posterior segment of the eye is made up of the vitreous humor, retina, choroid, sclera and optic nerve. Drug delivery to the posterior segment is very challenging because of the presence of anatomical and physiological barriers [24] .Author: Viral Tamboli, Sujay Shah, Ashim K. Mitra
https://www.sciencedirect.com/science/article/pii/S1818087620300659
In summary, transporter-targeted nano-drug delivery system (nano-DDS) has emerged as a promising nanoplatform for efficient drug delivery. The drug transporter can affect the absorption and metabolism of the drug in the body, thereby affecting the effectiveness of the drug; the down-regulation of the uptake transporter and the up-regulation of ...Author: Yi Peng, Lu Chen, Sheng Ye, Yu Kang, Junqing Liu, Su Zeng, Lushan Yu
https://www.frontiersin.org/articles/10.3389/fphar.2018.00027/full
Jan 26, 2018 · Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-surface receptors or transporters could enhance the efficacy of drug delivery and therapy. Transporters are expressed differentially on the cell-surface of different cell types, and also specific transporters are expressed at higher than normal levels in selective cell types under pathological ...Author: Longfa Kou, Longfa Kou, Yangzom D. Bhutia, Qing Yao, Zhonggui He, Jin Sun, Vadivel Ganapathy
https://www.researchgate.net/publication/305629969_Transporter_effects_on_cell_permeability_in_drug_delivery
Transporter effects on cell permeability in drug delivery. ... the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. ...
https://en.uit.no/go/target/338459/
The group aims at gaining a deeper understanding of transport processes of drugs in the body and its inter-relationship with drug delivery systems. The aim is the optimization of various drug dosage forms and delivery systems (advanced formulations) destined for oral, vaginal, parenteral and topical route of drug administration.
https://www.sigmaaldrich.com/technical-documents/articles/biofiles/intestinal-efflux-transporters.html
These novel intestinal efflux transporter knockout cell lines have been fully characterized and are proving to be powerful tools for elucidating drug-transporter interactions without dependence on chemical inhibitors and for clarifying the potential impact of specific efflux transporters in …
https://www.sigmaaldrich.com/technical-documents/articles/biofiles/liver-transporters-in-drug-drug-interactions.html
The Role of Liver Transporters in Drug-Drug Interactions. By: David C. Thompson, Ph.D, R&D Manager, Sigma ® Life Science and Michael D. Mitchell, Product Manager, Sigma ® …
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