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https://dimensionsofdentalhygiene.com/article/oral-use-transmucosal-drug-delivery/
Describe oral transmucosal drug delivery and the specific tissues that are the primary focus of this transmission route. List the advantages and limitations of this method of drug administration. Explain various forms of oral transmucosal delivery and clinical applications for this approach.
http://www.eurekaselect.com/114722/article
The transmucosal route includes oral, nasal, vaginal, and urethral and presents a challenge in the field of novel drug delivery technology. The oral transmucosal delivery, especially the buccal and sublingual routes have been explored successfully for a number of drugs in the last few decades with novel approaches emerging continuously.Author: Pooja Abhang, Munira Momin, Mayur Inamdar, Swapan Kar
https://medical-dictionary.thefreedictionary.com/transmucosal
transmucosal: [ trans″mu-ko´sal ] entering through, or across, a mucous membrane, as the administration of a drug via the cavity between the cheek and gum.
https://pediatrics.aappublications.org/content/100/1/143
The advantages of relatively rapid absorption offered by this drug delivery system make it a reasonable alternative to intravenous therapy. Some have argued that narcotics administered to children should have a disagreeable taste, precluding the use of this oral transmucosal drug delivery system. This tenet is …
https://www.fda.gov/drugs/data-standards-manual-monographs/route-administration
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https://www.contractpharma.com/issues/2013-01/view_features/transdermaltransmucosal-drug-delivery
Now we’re a soup-to-nuts provider in the transdermal space,” said Mr. Rensink. Producing oral dissolvable films for transmucosal drug delivery is also part of Tapemark’s new armory. “With our new investment we will be able to be fully integrated into that new technology as well.”
https://www.sciencedirect.com/science/article/pii/S0168365911000332
These transmucosal routes of drug delivery offer distinct advantages over per oral administration for systemic drug delivery such as the possible bypass of the first pass effect and avoidance of presystemic elimination within the GI tract . Amongst these, delivery of drugs to the oral cavity has attracted particular attention due to its ...Author: Viralkumar F. Patel, Fang Liu, Marc B. Brown
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680553/
Jul 15, 2019 · Non-invasive delivery of insulin was long considered the pinnacle of the drug delivery field, whereas today emphasis has switched to GLP-1 agonists and other peptides. This is not only because they are smaller and more amendable for transmucosal delivery, but also because they may have a higher therapeutic index.Author: Sam Maher, Luca Casettari, Lisbeth Illum
https://www.ukessays.com/essays/biology/advantages-of-transmucosal-route-biology-essay.php
INTRODUCTION: Among the various routes of the drug delivery, oral route is mostly favored by the patients and preferred by the clinicians. However, peroral (Jain.et.al.,2003) administrations of drugs have disadvantages such as hepatic first-pass metabolism and enzymatic degradation within the GI, which thus prohibits oral administration of certain classess of drugs.
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