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https://medical-dictionary.thefreedictionary.com/transmucosal+delivery
transmucosal delivery: ( trans-myū-kōsăl dĕ-livĕr-ē ) Drug delivery system wherein the drug traverses the intact mucosa.
http://www.eurekaselect.com/114722/article
The oral transmucosal delivery, especially the buccal and sublingual routes have been explored successfully for a number of drugs in the last few decades with novel approaches emerging continuously. The transmucosal membranes are relatively permeable, have a rich blood flow and hence allow the rapid uptake of a drug into systemic circulation to avoid first pass metabolism.Author: Pooja Abhang, Munira Momin, Mayur Inamdar, Swapan Kar
https://dimensionsofdentalhygiene.com/article/oral-use-transmucosal-drug-delivery/
Transmucosal drug delivery may allow dental teams to offer minimal sedation and more comfortable local injections. It also requires less equipment than some delivery methods, making it a cost-effective alternative. Yet, while there are advantages to this modality, there are also restrictions to developing drugs for transmucosal delivery.
https://pharm.ucsf.edu/desai/research/transmucosal-drug-delivery
Transmucosal Drug Delivery Mucous membranes lining the intestine are one physiological barrier to drug permeability. Our nanowire-coated materials dramatically increase particle adhesion and retention time of drug-delivery devices for more effective delivery through mucous membranes.
https://aquestive.com/innovative-drug-delivery-pharmfilm/transmucosal-expertise/
Transmucosal Expertise Advancing drug delivery Despite the number of advantages associated with transmucosal drug delivery, the number of medicines delivered as buccal or sublingual formulations remains relatively low. We believe in the potential for improving medicines through transmucosal delivery and work to make the possibilities real. 1
https://www.contractpharma.com/issues/2013-01/view_features/transdermaltransmucosal-drug-delivery
Transmucosal Delivery Systems The body’s mucous membranes occur primarily in the mouth and the nose. Their permeability — estimated at four to 4000 times that of the epidermis — allows for the systemic uptake of drugs painlessly and at a steady rate of delivery, bypassing the stomach environment and first-pass liver metabolism.
http://dds.pharmacy.psu.ac.th/index.php/researchs/181-r8.html
The research in transmucosal delivery is aimed to investigate novel pharmaceutical materials or formulations that contribute to the release both in vitro and in vivo at the target sites of action, as well as the stability of the drug.
https://www.sciencedirect.com/science/article/pii/S0168365911000332
These transmucosal routes of drug delivery offer distinct advantages over per oral administration for systemic drug delivery such as the possible bypass of the first pass effect and avoidance of presystemic elimination within the GI tract . Amongst these, delivery of drugs to the oral cavity has attracted particular attention due to its potential for high patient compliance and unique physiological features.Author: Viralkumar F. Patel, Fang Liu, Marc B. Brown
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680553/
Jul 15, 2019 · Drug delivery systems that safely and consistently improve transport of poorly absorbed compounds across epithelial barriers are highly sought within the drug delivery field. The use of chemical permeation enhancers is one of the simplest and widely tested approaches to improve transmucosal permeability via oral, nasal, buccal, ocular and pulmonary routes.Author: Sam Maher, Luca Casettari, Lisbeth Illum
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