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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://www.ncbi.nlm.nih.gov/pubmed/23921113
The article pays tribute to Prof. Robert Langer, who pioneered the engineering approach towards transdermal drug delivery. Over a period spanning nearly 25 years since his first publication in the field of transdermal drug delivery, Bob Langer has deeply impacted the field by quantitative analysis and innovative engineering.Author: S. Mitragotri
https://www.ncbi.nlm.nih.gov/pubmed/18997767
Prausnitz MR(1), Langer R. Author information: (1)School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr., Atlanta, Georgia 30332-0100, USA. [email protected] Transdermal drug delivery has made an important contribution to medical practice, but has yet to ...Author: Mark R Prausnitz, Robert Langer
http://drugdelivery.chbe.gatech.edu/Papers/2008/Prausnitz%20Nature%20Biotech%202008.pdf
Transdermal drug delivery Mark R Prausnitz 1 & Robert Langer 2 Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436072/
Jun 30, 2011 · Chemical enhancers, such as surfactants, are known to increase the rate of transdermal drug delivery by: i) increasing the stratum corneum lipid fluidity, ii) changing lipid organization,[ 116] iii) decreasing the path length and tortuosity across the stratum corneum, iv) …Author: Baris E. Polat, Douglas Hart, Robert Langer, Daniel Blankschtein
https://www.nature.com/articles/nbt.1504
Nov 07, 2008 · Abstract. Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://ki.mit.edu/people/faculty/langer/related
Team Uses Ultrasound to Boost Transdermal Drug Delivery. KI member Robert Langer is part of a team of MIT researchers that has combined two different frequencies of ultrasound waves to make the skin more permeable to therapeutics. The technology could pave the way for noninvasive drug delivery or needle-free vaccinations, and may enhance the ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725305/
Transdermal drug delivery. The top layer of the skin, the stratum corneum (SC), is a formidable diffusion barrier. Compared to oral drug delivery, transdermal drug delivery (TDD) allows circumvention of the first-pass effect and the delivery of drugs with low oral bioavailability without the risk of …Author: Matthias A Oberli, Carl M Schoellhammer, Robert Langer, Daniel Blankschtein
https://www.researchgate.net/publication/261759007_TRANSDERMAL_DRUG_DELIVERY_SYSTEM_A_REVIEW
An advantage of a transdermal drug delivery route over other types of delivery systems such as oral, topical, intravenous, intramuscular, etc. is that the patch may essentially can provide a controlled release of the medication into the patient, usually through either a porous membrane covering...
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