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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066337/
Mar 03, 2011 · Transdermal delivery of peptides and proteins avoids the disadvantages associated with the invasive parenteral route of administration and other alternative routes such as the pulmonary and nasal routes. Since proteins have a large size and are hydrophilic ...Author: Haripriya Kalluri, Ajay K. Banga
https://www.researchgate.net/publication/268184955_Macroflux_Technology_for_Transdermal_Delivery_of_Therapeutic_Proteins_and_Vaccines
Request PDF On Nov 7, 2002, Michel Cormier and others published Macroflux Technology for Transdermal Delivery of Therapeutic Proteins and Vaccines Find, read and cite all …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal delivery represents an attractive alternative to oral delivery of drugs and is poised to provide an alternative to hypodermic injection too 1 – 4.For thousands of years, people have placed substances on the skin for therapeutic effects and, in the modern era, a variety of topical formulations have been developed to treat local indications.Author: Mark R Prausnitz, Robert Langer
https://www.sciencedirect.com/science/article/pii/S0167779909001437
Therapeutic application of peptides and proteins: parenteral forever? ... therapeutic vaccines for immunization against hepatitis A and/or B, ... In addition to peptides, the feasibility of transdermal delivery for proteins, such as interferon α, is also being investigated.Author: Zuzana Antosova, Martina Mackova, Vladimir Kral, Tomas Macek
https://www.researchgate.net/publication/50268554_Transdermal_Delivery_of_Proteins
The one most important barrier for efficient delivery of therapeutic proteins via transdermal route is skin itself [206]. Skin prevents the absorption of externally applied substances due to its ...
https://www.sciencedirect.com/science/article/pii/B9780123849359100045
Transdermal delivery offers a potential alternative, overcoming setbacks associated with oral as well as injectable formulations. The passive delivery of proteins through the skin has to date been impracticable due to their macromolecular and hydrophilic nature, which limits their transport through the lipophilic skin barrier (stratum corneum).Author: Anushree Herwadkar, Ajay K. Banga
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