Transdermal Delivery Of Cyclosporin A Using Electroporation

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Transdermal delivery of cyclosporin-A using electroporation

    https://www.sciencedirect.com/science/article/pii/S016836599700117X
    We have attempted to study different electroporation parameters to help understand the technique, and arrive at an optimized delivery condition. This is also the first report of the use of hydro alcoholic solution as the donor solution for the transdermal delivery using electroporation.Author: Su Wang, M Kara, T.R Krishnan

(PDF) Transdermal Delivery of Macromolecules Using Skin ...

    https://www.researchgate.net/publication/12600465_Transdermal_Delivery_of_Macromolecules_Using_Skin_Electroporation
    Transdermal Delivery of Macromolecules Using Skin Electroporation. ... The transdermal delivery by skin electroporation of FITC and FD 4.4 was equivalent whereas transport of higher molecular ...

Skin electroporation for transdermal and topical delivery ...

    https://www.sciencedirect.com/science/article/pii/S0169409X03002436
    In this paper, studies on transdermal and topical drug delivery using electroporation are reviewed with emphasis on potential clinical applications. Efficacy of transport by skin electroporation alone or in combination with other methods and safety issues are discussed. 2. Mechanism of transdermal drug transport by electroporation 2.1.Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat

Electroporation for Dermal and Transdermal Drug Delivery ...

    https://link.springer.com/chapter/10.1007/978-3-662-53273-7_7
    May 05, 2017 · Wang S, Kara M, Krishnan TR (1998) Transdermal delivery of cyclosporin-A using electroporation. J Control Release 50:61–70 PubMed CrossRef Google Scholar Wang RJ, Huang YB, Wu PC, Fang JY, Tsai YH (2007) The effects of iontophoresis and electroporation on transdermal delivery of indomethacin evaluated in vitro and in vivo.Author: Babu M. Medi, Buddhadev Layek, Jagdish Singh

Skin Electroporation for Transdermal and Topical Drug Delivery

    https://www.researchgate.net/publication/290802375_Skin_Electroporation_for_Transdermal_and_Topical_Drug_Delivery
    A number of studies have used electroporation for enhancement of transdermal drug delivery using different pulse protocols, with theo- retical and experimental approaches used to explain the ...

Transdermal drug delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
    Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer

Transdermal Cyclosporine for Cats Clinician's Brief

    https://www.cliniciansbrief.com/article/transdermal-cyclosporine-cats
    Jun 01, 2014 · Transdermal cyclosporine delivery may minimize problems with oral administration (eg, GI upset). In this crossover study, oral and transdermal blood concentrations of cyclosporine were compared. Cats (n = 6) received oral cyclosporine (5 mg/kg) for 7 days; whole blood was collected on the last day at 2 and 12 hours postadministration.

Mechanism of Transdermal Drug Delivery by Electroporation ...

    https://link.springer.com/protocol/10.1385%2F1-59259-080-2%3A187
    Human skin is a complex system, providing a formidable obstacle to drug delivery Fig. 1 (1, 2, 3). In particular, the stratum corneum (SC) is the primary barrier to transdermal drug delivery. The...Author: Timothy E. Vaughan, James C. Weaver

Skin electroporation for transdermal and topical delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/15019751
    Mar 27, 2004 · Electroporation is the transitory structural perturbation of lipid bilayer membranes due to the application of high voltage pulses. Its application to the skin has been shown to increase transdermal drug delivery by several orders of magnitude.Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat

Transdermal delivery of cyclosporin A by electrically ...

    http://research.library.mun.ca/12311/
    Transdermal drug delivery has recently received increasing attention in the face of growing challenges to deliver peptide and protein drugs. Controlled transdermal delivery is an important route for the delivery of peptides and proteins that can maintain the therapeutic effectiveness of the drug by minimizing enzymatic degradation which is a major concern in other noninvasive routes of ...Author: Su Wang

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