We have collected information about Transbuccal Drug Delivery for you. Follow the links to find out details on Transbuccal Drug Delivery.
https://www.sciencedirect.com/science/article/pii/S037851731100874X
Similar to skin, the buccal route is also an attractive alternative for non invasive systemic delivery of drugs. Compared to oral drug delivery, transbuccal drug delivery provides great advantages such as a much milder environment for drug absorption, elimination of first-past metabolism, rapid drug uptake, and improved patient compliance.Author: Longsheng Hu, Sérgio M.C. Silva, Sérgio M.C. Silva, Bassam B. Damaj, Richard Martin, Bozena B. Michn...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167456/
Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation Mohamed A El-Nabarawi , 1 Adel A Ali , 2 Heba M Aboud , 2 Amira H Hassan , 2 and Amany H Godah 2Author: Mohamed A El-Nabarawi, Adel A Ali, Heba M Aboud, Amira H Hassan, Amany H Godah
https://rucore.libraries.rutgers.edu/rutgers-lib/30081/PDF/1/play/
Transbuccal drug delivery systems are still at research stage. The major barriers to transdermal and transbuccal drug delivery are stratum corneum of skin and epithelium of buccal tissue. The objective of this work was to overcome these barriers to significantly enhance transdermal and transbuccal delivery
http://www.eurekaselect.com/114722/article
This route of drug delivery offers a number of benefits over other drug delivery approaches and allows drugs to circumvent some of the body’s natural defense mechanisms like first pass metabolism, harsh stomach environment etc.Author: Pooja Abhang, Munira Momin, Mayur Inamdar, Swapan Kar
https://rucore.libraries.rutgers.edu/rutgers-lib/30081/
The major barriers to transdermal and transbuccal drug delivery are stratum corneum of skin and epithelium of buccal tissue. The objective of this work was to overcome these barriers to significantly enhance transdermal and transbuccal delivery of hydrophilic drugs without causing major damage to skin and buccal tissue.
https://www.sciencedirect.com/science/article/pii/S0378517310008288
It is most probable that iontophoresis enhanced transbuccal drug delivery through disordering of the outer epithelial cell layers, i.e. more of the paracellular route (Jacobsen, 2001) similar to disrupting porcine stratum corneum and increasing intercellular space for enhancing transdermal drug delivery (Bhatia et al., 1997, Singh et al., 1998).Author: Longsheng Hu, Bassam B. Damaj, Richard Martin, Bozena B. Michniak-Kohn
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