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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695828/
Oct 22, 2015 · In delivery systems involving transdermal patches, the drug is stored in a reservoir (reservoir type) or drug dissolved in a liquid or gel-based reservoir (matrix type).The starting point for the evaluation of the kinetics of drug release from a transdermal patch is an estimation of the drug compound’s maximum flux across the skin (flux (J ...Author: Ahlam Zaid Alkilani, Maelíosa T.C. McCrudden, Ryan F. Donnelly
http://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
ABSTRACT: A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. Often, this promotes healing to an injured area of the body. An advantage of a transdermal drug delivery route over other types of medication delivery such as oral, topical, intravenous, intramuscular, etc. is that the patch ...
https://academic.oup.com/bjaed/article/7/5/171/535087
Oct 01, 2007 · Pharmacokinetics of transdermal drug delivery. The drug is stored in the TDDS either in a reservoir or impregnated into the fabric of the patch. On applying the TDDS to the skin, a drug concentration gradient is developed and the drug starts to move down the gradient. A second drug reservoir is established in the stratum corneum.Author: Lyn Margetts, Richard Sawyer
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