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https://www.future-science.com/doi/full/10.4155/tde.12.120
Nov 23, 2012 · 7 du Plessis L, Kotze A, Junginger H. Nasal and rectal delivery of insulin with chitosan and N-trimethyl chitosan chloride. Drug Deliv. 17,399–407 (2010).Crossref, Medline, CAS, Google Scholar; 8 Agrawal AK, Gupta PN, Khanna A et al. Development and characterisation of in situ gel system for nasal insulin delivery. Pharmazie 65,188–193 (2010).Author: Hamde Nazar, John Tsibouklis
https://www.researchgate.net/publication/233972569_Towards_the_nasal_delivery_of_insulin
Towards the nasal delivery of insulin. ... effect of chitosan in solution or powder form and that chitosan powder was the most effective for mulation for nasal delivery of insulin in the sheep ...
https://www.future-science.com/doi/pdfplus/10.4155/tde.12.120
Towards the nasal delivery of insulin “With several reports pointing to the figure of 17% bioavailability, the insulin delivery community needs to debate whether current nasal delivery technologies have evolved sufficiently to merit evaluation in the clinic.” Hamde Nazar Department of …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
Insulin delivery methods: Past, present and future. ... NASAL INSULIN. In theory, intranasal delivery has several advantages over oral (bypass GI peptidases), ... From this subcutaneous pocket, the peritoneum is opened, and the tip of the catheter is carefully inserted and directed towards the liver.
https://www.ncbi.nlm.nih.gov/pubmed/23259244
1. Ther Deliv. 2012 Nov;3(11):1241-3. Towards the nasal delivery of insulin. Nazar H, Tsibouklis J. PMID: 23259244 [PubMed - indexed for MEDLINE]Author: Hamde Nazar, John Tsibouklis
https://www.mdsabstracts.org/abstract/intranasal-delivery-of-insulin-for-the-restoration-of-memory-signaling-in-alzheimer-disease/
Jun 06, 2017 · Chitosan coating elicits associated benefits in addition to prolonging uptake via intranasal route. This project may provide sound platform towards employment of this modified nanoparticulate carrier for brain delivery of proteins and peptides towards intranasal delivery of insulin for restoration of memory signaling in Alzheimer patients.
https://www.in-pharmatechnologist.com/Article/2007/05/23/New-insulin-product-takes-the-nasal-route
New insulin product takes the nasal route. ... has recently been directing its expertise towards an intranasal insulin product amid growing interest in alternative insulin delivery techniques that avoid the traditional needle-based approach. Although nasal drug delivery systems have been around for a while, there have been limitations in the ...
https://www.researchgate.net/publication/321466365_Nose-to-brain_delivery_of_insulin_enhanced_by_a_nanogel_carrier
These results show insulin delivery to the brain by intranasal administration can be modified with agents such as albumin, may be dependent on the insulin receptor, and is not affected by an AD ...
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticle-insulin-drug-delivery-applications-and-new-aspects
2.2. Nasal delivery. Nasal administration has attracted a lot of interest as a highly efficient route for the systemic delivery of insulin. It has been well known that the pharmacokinetic profile of intranasal insulin resembles the pulsatile pattern of endogenous insulin secretion in healthy volunteers during meal times .Author: Hatice Kübra Elçioğlu, Ali Demir Sezer
https://core.ac.uk/display/44331205
Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): https://researchportal.port.ac... (external link) https ...Author: H. Nazar and John Tsibouklis
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