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https://clinicalgate.com/topical-and-transdermal-drug-delivery/
Aug 02, 2015 · • Topical drug delivery treats a local disorder and aims to retain the active pharmaceutical ingredient within the skin. • Transdermal drug delivery the skin to deliver the drug to the systemic circulation. • Skin is a complex multi-layered membrane but the outermost layer, the stratum corneum, provides the principal barrier to drug delivery.
https://www.sciencedirect.com/science/article/pii/B9780815520252100010
Transdermal delivery is the term that is confined to a situation in which the drug diffuses through different layers of the skin into systemic circulation to elicit the therapeutic response (Brown et al., 2006).An example would be management of hypertension using a transdermal clonidine patch.Author: S. Narasimha Murthy, H.N. Shivakumar
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal delivery represents an attractive alternative to oral delivery of drugs and is poised to provide an alternative to hypodermic injection too 1 – 4.For thousands of years, people have placed substances on the skin for therapeutic effects and, in the modern era, a variety of topical formulations have been developed to treat local indications.Author: Mark R Prausnitz, Robert Langer
https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
3.4.1 Transdermal Drug Delivery System. Electrospun NFs can also be utilized as a transdermal drug delivery system (TDDS). A TDDS is designed to facilitate delivery through the skin. It is an alternative way of delivering sensitive drugs that are greatly affected by first-pass metabolism.
https://www.ncbi.nlm.nih.gov/pubmed/30714524
Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies. Benson HAE(1), Grice JE(2), Mohammed Y(2), Namjoshi S(2), Roberts MS(2)(3). Author information: (1)School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University of Technology, Perth, Australia.Author: Heather A.E. Benson, Jeffrey E. Grice, Yousuf Mohammed, Sarika Namjoshi, Michael S. Roberts
https://www.lubrizol.com/en/Life-Sciences/Pharmaceuticals/Topical-and-Transdermal-Drug-Delivery
Topical and Transdermal Drug Delivery. Lubrizol offers a variety of solutions for safe contact with the skin. These include topical and transdermal applications. Topical. Lubrizol is a leading supplier of excipients for medicated topical formulations. We support both over-the-counter and prescription, topical drug formulations.
https://www.researchgate.net/publication/285954404_Ethosomes_for_transdermal_and_topical_drug_delivery
For transdermal and topical drug delivery system to be effective, the drug must obviously be able to penetrate the skin barrier and reach the target site [1]. During the past several decades ...
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118140505
Dec 07, 2011 · Practical drug development approaches presented by leading experts. Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products.
https://www.amazon.com/Topical-Transdermal-Drug-Delivery-Principles/dp/0470450290
Practical drug development approaches presented by leading experts. Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products.Author: Heather A. E. Benson
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