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https://www.meddeviceonline.com/doc/what-s-next-in-inhalation-drug-delivery-0001
Jan 10, 2017 · While each device has its own unique combination of device design and drug formulation, all inhalation devices share some common challenges. Drug formulation and aerosolization — Inhalation devices must be thought of as combination products. In fact, inhalation delivery is a three-part system consisting of the user, the device, and the drug.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/inhalation-device
While there are numerous different inhaler devices in clinical use, three types of devices are routinely used to deliver inhalable medications: pressurized metered dose inhalers (pMDIs), dry powder inhalers (DPIs), and nebulizers. More recently, a new type of device, the Respimat soft mist inhaler (SMI), has also been developed.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · Inhalation therapy was practiced by ancient civilizations in Egypt, Greece, India, and People’s Republic of China as evidenced by different artifacts displayed in museums, that may be considered the first used inhalation devices.1,2. Currently, inhalation therapy is the best option for lung diseases like asthma, cystic fibrosis, and chronic ...Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884297/
Apr 18, 2002 · Pulmonary delivery devices. The lung has served as a route of drug administration for thousands of years. The origin of inhaled therapies can be traced back 4000 years ago to India, where people smoked the leaves of the Atropa belladonna plant to suppress cough. In the 19th and early 20th centuries, asthmatics smoked asthma cigarettes that contained stramonium powder mixed with …Author: N. R. Labiris, M. B. Dolovich
https://adc.bmj.com/content/82/3/185
Mar 01, 2000 · Drug delivery device. There are three main types of inhalation drug delivery device, grouped by the drug dispersion method that they use: pressurised metered dose inhalers, containing a mixture of propellant and drug under pressure; dry powder inhalers, utilising the patient's inspiratory effort to disperse medication; and nebulisers, using compressed gas or the vibration of a piezo electric ...Author: Chris O'callaghan, Peter W Barry
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2044.2007.05026.x
Mar 14, 2007 · The maximum oxygen concentrations were recorded for the devices at 10, 15, 20 and 30 breaths.min −1. The variable performance devices were tested at oxygen flow rates of 2, 4, 6, 8, 10 and 15 l.min −1 as delivered by an AHE ball flow meter. The fixed performance devices were assessed using the oxygen flow rates for the appropriate inserts ...Author: T. A. J. Wagstaff, N. Soni
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