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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
1. Mechanisms of Ultrasonic-Enhanced Drug Delivery. Ultrasound (US) has been employed to enhance the delivery and activity of drugs for the past two decades. In the past 6 years, however, research in US-activated drug delivery has blossomed with the introduction of gas bubbles.Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
https://www.frontiersin.org/articles/10.3389/fbioe.2019.00324/full
Taken together, ultrasound-based drug delivery enhances efficacy of cancer treatment by improving the cellular uptake of nanoparticles, enhancing penetration of nanoparticles in tumor, and increasing the therapeutic delivery of the drug (by disruption of the particles on the site of action) (Hare et al., 2017).Author: Priyanka Tharkar, Ramya Varanasi, Wu Shun Felix Wong, Craig T. Jin, Wojciech Chrzanowski
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/med.10004
The purpose of this review is to summarize some of the recent advances made in the area of therapeutic ultrasound as they relate to drug delivery. In particular, this review will focus on the applications of ultrasound to enhance the delivery and effect of three distinctive therapeutic drug classes: chemotherapeutic, thrombolytic, and gene‐based drugs.Author: Ka-yun Ng, Yang Liu
https://www.scitecheuropa.eu/therapeutic-ultrasound-network/87359/
The UK’s Engineering and Physical Sciences Research Council (EPSRC) has funded a network, the Therapeutic Ultrasound Network for Drug Delivery and Ablation Research (ThUNDDAR), the main focus of which is to inform the clinical community of the existence of therapy ultrasound techniques and to stimulate the translational research that will enable their potential to be fully realised.Author: Michaela Adams
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883936/
The average ultrasound frequency utilized in drug delivery varies from kilohertz to Megahertz levels. It depends on the type of cells and the model animal selected for the particular experiment. Typically, the ultrasound frequency used for drug delivery and other therapeutic applications, is lesser than diagnostic purpose.Author: Priyanka Tharkar, Ramya Varanasi, Wu Shun Felix Wong, Craig T. Jin, Wojciech Chrzanowski
https://www.ebme.co.uk/articles/clinical-engineering/therapeutic-ultrasound
Therapeutic ultrasound assisted brain drug delivery or Acoustic Targeted Drug Delivery is currently being studied to enhance the success of chemotherapy treatments to brain cancer cells. Scientists are using Therapeutic Ultrasound to increase the distribution of chemical dye agents into brain tissue, to help brain tissue absorb chemotherapy drugs faster.
https://www.nature.com/articles/nrd1662
Mar 01, 2005 · Therapies described above use ultrasound to facilitate the action of another agent (drug, DNA or enzyme). However, ultrasound in itself is capable of inducing biological effects that have therapeutic implications. For example, ultrasound is used to facilitate the healing of wounds in skin, muscle and other tissues.Author: Samir Mitragotri
https://www.researchgate.net/publication/337451792_Nano-Enhanced_Drug_Delivery_and_Therapeutic_Ultrasound_for_Cancer_Treatment_and_Beyond
Nov 22, 2019 · While ultrasound is most widely known for its use in diagnostic imaging, the energy carried by ultrasound waves can be utilized to influence cell function and drug delivery. Consequently, our...
https://www.currentmedicinalchemistry.com/articles/179255/applications-of-micronanotechnology-in-ultrasound-based-drug-delivery-and-therapy-for-tumor
Ultrasound has been broadly used in biomedicine for both tumor diagnosis as well as therapy. The applications of recent developments in micro/nanotechnology promote the development of ultrasound-based biomedicine, especially in the field of ultrasound-based drug delivery and tumor therapy.
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Other NIBIB-funded researchers are developing a system of drug delivery using a type of bacteria that has a two-part navigation system—magnetic and oxygen sensing. They have tested the delivery system in mice, achieving a remarkable success delivering drugs …
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