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https://www.sciencedirect.com/science/article/pii/S0014299909008759
The α-helical coiled coil is the most frequently encountered subunit oligomerization motif found in proteins (Cohen and Parry, 1990, Lupas, 1996, Kohn et al., 1997), with an analysis of the protein database revealing that approximately 10% of all proteins contain the signature heptad repeat (abcdefg) n which is characteristic of coiled-coil proteins (Walshaw and Woolfson, 2001).Author: Ainsley A. McFarlane, George L. Orriss, Jörg Stetefeld
https://www.researchgate.net/publication/38017059_The_use_of_coiled-coil_proteins_in_drug_delivery_systems
Coiled-coil proteins such as COMPcc are attractive candidates for the design of drug delivery systems [10, 28,29,30]. In this work we have studied the hydrophobic binding pocket of COMPcc and have ...
https://www.deepdyve.com/lp/elsevier/the-use-of-coiled-coil-proteins-in-drug-delivery-systems-x68yjQUlkP
Dec 25, 2009 · The use of coiled-coil proteins in drug delivery systems The use of coiled-coil proteins in drug delivery systems McFarlane, Ainsley A.; Orriss, George L.; Stetefeld, Jörg 2009-12-25 00:00:00 The coiled-coil motif is found in approximately 10% of all protein sequences and is responsible for the oligomerization of proteins in a highly specific manner.
https://www.sciencedirect.com/science/article/pii/S0734975012000055
The coiled coil is a superhelical structural protein motif that has been thoroughly investigated in recent years. Because of the relatively well-understood principles that determine the properties of coiled coil peptides and proteins, macromolecular systems containing the coiled coil motif have been suggested for various applications.Author: Michal Pechar, Robert Pola
https://www.researchgate.net/publication/221767679_The_coiled_coil_motif_in_polymer_drug_delivery_systems
The coiled coil motif in polymer drug delivery systems. ... As one of the most important motifs underlying many of the functionalities found in natural proteins, coiled-coil helix bundles present ...
https://www.nature.com/articles/17092
Feb 04, 1999 · The coiled coil 18, a left-handed superhelix of two or more right-handed α-helices, has been identified in proteins ranging from muscle proteins to DNA transcription factors.It has the ...Author: Chun Wang, Russell J. Stewart, JindŘich KopeČek
https://www.nature.com/articles/s41467-019-10578-2
Jun 28, 2019 · Design and characterisation of the coiled coil proteins. a TEM image of magnetosomes inside an M. magneticum AMB-1 cell (scale bar is 100 nm) and b a schematic of the magnetosome membrane and ...Author: Andrea E. Rawlings, Andrea E. Rawlings, Lori A. Somner, Michaela Fitzpatrick-Milton, Thomas P. Roebu...
https://pubs.acs.org/doi/10.1021/bm500436p
Coiled coils are a common structural motif in many natural proteins that can also be utilized in the design and preparation of drug delivery systems for the noncovalent connection of two macromolecules. In this work, two different pairs of peptides forming coiled coil hetero-oligomers were designed, synthesized, and characterized.Author: Michal Pechar, Robert Pola, Richard Laga, Alena Braunová, Sergey K. Filippov, Anna Bogomolova, Lucie...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745713/
Background. Coiled-coil domain containing 34 (CCDC34) promotes cell proliferation and invasive properties in human cancer. The aim of this study was to compare the expression of CCDC34 in pancreatic adenocarcinoma with normal pancreatic tissue, and to evaluate the prognostic significance of CCDC34 expression in patients with pancreatic adenocarcinoma, using bioinformatics.Author: Wei Qi, Feng Shao, Qiang Huang
https://www.future-science.com/doi/10.4155/tde.15.19
Jul 07, 2015 · The use of coiled-coil proteins in drug delivery systems. Eur. J. Pharmacol. 625 ... Comparison of the structures and stabilities of coiled-coil proteins containing hexafluoroleucine and t-butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side-chains.Author: Joseph A Frezzo, Jin Kim Montclare
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