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https://www.researchgate.net/publication/223742252_The_role_of_g-scintigraphy_in_oral_drug_delivery
The role of γ-scintigraphy in oral drug delivery. ... Neutron activation of Sm-152 offers a method of radiolabeling for the in vivo study of oral dose formulations by gamma scintigraphy ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/gamma-scintigraphy
Gamma scintigraphy is noninvasive technique that gives information about integrity, dispersion, or release characteristics of the radiolabeled delivery system (Marvola et al., 2008). In nuclear medicine, after the administration of radiopharmaceutical, emitted radiation is detected by a …
https://www.ddw-online.com/enabling-technologies/p149555-in-vivo-imaging-in-drug-development-gamma-scintigraphy-summer-12.html
For the past 12 years Alyson has fulfilled the role of Senior Research Fellow at Quotient Clinical, a provider of early drug development services. As lead scientist she is responsible for all oral scintigraphic studies performed and is an acknowledged expert in the use of scintigraphy to assess product performance and pharmacodynamic effect.
https://www.sciencedirect.com/science/article/pii/S1461534799001522
Gamma scintigraphy plays a key role in the assessment of pulmonary drug delivery, both for drugs used in the treatment of asthma and for medicines intended for systemic delivery via the lungs7, 8. The quantity of drug deposited in the lungs can be quantified precisely through the use of this technique9, 10.Author: Stephen P. Newman, Ian R. Wilding
https://www.researchgate.net/publication/11052047_Bioequivalence_Testing_for_Locally_Acting_Gastrointestinal_Products_What_Role_for_Gamma_Scintigraphy
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874431/
Gamma scintigraphy is an ideal noninvasive technique for obtaining information on the gastrointestinal transit of a dosage form [6, 7]. A stable, nonradioactive isotope, such as 152 samarium oxide, is incorporated in the test formulation, and subsequently activated to a specific level of radioactivity by neutron bombardment in a nuclear reactor.Author: Bharat Damle, Ismat Ullah, Walter Doll, Gary Wiley, Catherine Knupp
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