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https://www.sciencedirect.com/science/article/pii/037851739090108G
Strategies for the controlled parenteral delivery of polypeptides and proteins are reviewed. The different approaches are divided into five classes: (a) hydrogels, (b) self-diffusion systems, (c) microparticles, (d) biodegradable polymers, and (e) porous membranes; self-regulated delivery represents an additional subset.Author: C.G. Pitt
https://www.sciencedirect.com/science/article/pii/0169409X93900478
A number of reviews covering the controlled parenteral delivery of peptides and proteins have been published [5-7]. Implants capable of releasing peptides or proteins in a controlled manner for the desired length of time is clearly a very-high-priority objective.Author: Jorge Heller
https://www.researchgate.net/publication/6537168_Controlled_Delivery_of_Peptides_and_Proteins
Controlled Delivery of Peptides and Proteins. The final aim/target of Pharmaceutical Sciences is to design successful dosage forms for effective therapy, …
https://www.sciencedirect.com/science/article/pii/B9780123849649000116
11 - Parenteral Delivery of Peptides and Proteins. ... Polymers are an integral part of many parenteral controlled release particulate systems. For use in the body, these polymers must be biocompatible and preferably biodegradable. ... To formulate an effective parenteral delivery system for proteins and peptides, the pharmacokinetic profile of ...Author: Himanshu Agrawal, Nipa Thacker, Ambikanandan Misra
https://www.sciencedirect.com/science/article/pii/0169409X93900467
Among them, micro- and nanoparticles have been proposed for the safe and controlled parenteral administration of peptides and proteins. The main advantage of these microdispersed polymeric systems is their easy administration by a single injection, whereas other controlled-release dosage forms larger in size may require surgical incision.Author: P. Couvreur, F. Puisieux
https://www.sciencedirect.com/science/article/pii/016836599290014I
Only few parenteral depot formu- lations of peptides or proteins have entered clin- ical testing or are commercially available, most of them being agonists or antagonists of lutein- izing hormone-releasing hormone LH-RH [ 3-7 ]. We studied design factors affecting release ofoc- treotide and bovine serum albumin from micro- spheres and implants.Author: D. Bodmer, T. Kissel, E. Traechslin
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