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https://onlinelibrary.wiley.com/doi/pdf/10.1211/0022357011775145
ISSN 0022-3573 The biopharmaceutical aspects of nasal mucoadhesive drug delivery Michael Ikechukwu Ugwoke, Norbert Verbeke, Renaat Kinget Abstract Nasal drug administration has frequently been proposed as the most feasible alternative to parenteral injections. This is due to the high permeability of the nasal epithelium, allowing aAuthor: Michael Ikechukwu Ugwoke, Norbert Verbeke, Renaat Kinget
https://www.onlinelibrary.wiley.com/doi/full/10.1211/0022357011775145
Nasal mucoadhesion as a promising method of nasal absorption enhancement is discussed, and factors that influence mucoadhesion, as well as safety of nasal mucoadhesive drug delivery systems are reviewed in detail. Nasal drug administration is presently mostly used for local therapies within the nasal cavity.Author: Michael Ikechukwu Ugwoke, Norbert Verbeke, Renaat Kinget
https://www.researchgate.net/publication/12125399_The_biopharmaceutical_aspects_of_nasal_mucoadhesive_drug_delivery
Nasal mucoadhesion as a promising method of nasal absorption enhancement is discussed, and factors that influence mucoadhesion, as well as safety of nasal mucoadhesive drug delivery systems are reviewed in detail. Nasal drug administration is presently mostly used for local therapies within the nasal cavity.
https://www.academia.edu/6808549/The_biopharmaceutical_aspects_of_nasal_mucoadhesive_drug_delivery
The biopharmaceutical aspects of nasal mucoadhesive drug delivery
https://www.deepdyve.com/lp/wiley/the-biopharmaceutical-aspects-of-nasal-mucoadhesive-drug-delivery-FBpiLKPwrX
Jan 01, 2001 · The biopharmaceutical aspects of nasal mucoadhesive drug delivery This is due to the high permeability of the nasal epithelium, allowing a higher molecular mass cut‐off at approximately 1000 Da, and the rapid drug absorption rate with plasma drug profiles sometimes almost identical to those from intravenous injections.
https://www.nature.com/articles/nrd.2018.183
Nov 30, 2018 · Although most of the successful biologics to date are drugs that bear a peptidic backbone, ranging from small peptides to monoclonal antibodies (~500 residues; 150 kDa), new biologic modalities, such as nucleotide-based therapeutics and viral gene therapies, are rapidly maturing towards widespread clinical use.Author: Aaron C. Anselmo, Yatin Gokarn, Samir Mitragotri
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