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https://www.sciencedirect.com/science/article/pii/S0168365907004154
Thus, to develop a photothermal modulated drug delivery system, we have fabricated nanoshell-composite hydrogels in which SiO 2 –Au nanoshells of varying concentrations have been embedded within temperature-sensitive hydrogels, for the purpose of initiating a temperature change with light.Author: Malavosklish Bikram, Andre M. Gobin, Rachel E. Whitmire, Jennifer L. West
https://www.researchgate.net/publication/5925235_Temperature_sensitive-hydrogel_with_SiO2-Au_nanoshell_s_for_controlled_drug_delivery
Temperature sensitive-hydrogel with SiO2–Au nanoshell s for controlled drug delivery Article in Journal of Controlled Release 123(3):219-27 · December 2007 with 46 Reads How we measure 'reads'
https://scholars.duke.edu/individual/pub738904
Thus, to develop a photothermal modulated drug delivery system, we have fabricated nanoshell-composite hydrogels in which SiO(2)-Au nanoshells of varying concentrations have been embedded within temperature-sensitive hydrogels, for the purpose of initiating a temperature change with light.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808249/
Nanoshells have been tested for drug delivery. In one early study, composites of hydrogels and gold nanoshells were developed for photothermally-modulated drug delivery (Sershen et al 2000). Irradiation at 1064 nm was absorbed by the nanoshells and converted to heat, which led to the collapse of the hydrogel thus significantly enhancing the ...
https://scholars.duke.edu/person/jennifer.l.west
Jennifer L West Fitzpatrick Family University Distinguished Professor of Engineering. Jennifer West’s research in biomaterials and tissue engineering involves the synthesis, development, and application of novel, biofunctional materials, and the use of biomaterials and engineering approaches to …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565577/
Aug 10, 2015 · Nanoparticle drug delivery carriers that can modulate drug release based on an exogenous signal, such as light, are of great interest, especially for improving cancer therapy. ... West J. L. Temperature-sensitive hydrogels with SiO2-Au nanoshells for controlled drug delivery. J. Controlled Release 2007, 123, ...Author: Laura E. Strong, Jennifer L. West
https://www.osapublishing.org/oe/abstract.cfm?URI=oe-16-24-19579
The spectral and angular radiation properties of gold-silica-gold multilayer nanoshells are investigated using Mie theory for concentric multilayer spheres. The spectral tunability of multilayer nanoshells is explained and characterized by a plasmon hybridization model and a universal scaling principle. A thinner intermediate silica layer, scaled by particle size, red shifts the plasmon ...
https://link.springer.com/article/10.1007/s13404-016-0188-2
Nov 22, 2016 · Gold nanoshells are particles usually composed of a spherical silica core coated with a thin gold layer. Their chemical and optical properties make them suitable and attractive for medical applications, namely cancer treatment and diagnosis, as they have been studied for biosensing, imaging, and photothermal ablation. For their synthesis, most of the reported methods are based on the first ...Author: Mariano J. García-Soto, Omar González-Ortega
https://www.hindawi.com/journals/amse/2019/9358740/
The scattering and absorption efficiencies of light by a single silicon/silica/gold spherical multishell in biological tissues are analyzed theoretically in the framework of Lorenz–Mie theory and finite-difference time-domain formalism. We first revised the ideal case of a concentric silicon/gold nanoshell, analyzed the effect of growing a silica layer of uniform thickness around the silicon ...Author: Wajdi Chaabani, Abdallah Chehaidar, Julien Proust, Jérôme Plain
https://www.cd-bioparticles.com/support/properties-and-applications-of-gold-nanoshells.html
Gold nanoshells have a range of attractive optical, chemical, and physical properties that help cancer detection, treatment, and medical biosensing. Nanoshells can vary over the spectral range spanning the visible and near-infrared (NIR) regions. In the "tissue window" of the near infrared region, light entering the tissue is optimal.
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