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https://www.nature.com/articles/s41467-018-03705-y
Apr 12, 2018 · Introduction Approaches for targeted delivery of therapeutics in cancer typically involves systemic administration of therapeutics packaged in nanocarriers (NCs) or localized delivery of...Author: Daniel Rosenblum, Nitin Joshi, Nitin Joshi, Wei Tao, Jeffrey M. Karp, Jeffrey M. Karp, Dan Peer
https://www.ncbi.nlm.nih.gov/pubmed/30102295
1. Nat Biotechnol. 2018 Oct;36(9):847-856. doi: 10.1038/nbt.4195. Epub 2018 Aug 13. Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.Author: Sarwish Rafiq, Oladapo O Yeku, Hollie J Jackson, Terence J Purdon, Dayenne G van Leeuwen, Dylan J Dr...
https://www.ncbi.nlm.nih.gov/pubmed/29650952
Apr 12, 2018 · Targeted delivery approaches for cancer therapeutics have shown a steep rise over the past few decades. However, compared to the plethora of successful pre-clinical studies, only 15 passively targeted nanocarriers (NCs) have been approved for clinical use and none of the actively targeted NCs have advanced past clinical trials.Author: Daniel Rosenblum, Nitin Joshi, Nitin Joshi, Wei Tao, Jeffrey M. Karp, Jeffrey M. Karp, Dan Peer
https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.8b01342
Together, these results suggest that NNPs/CLT represent a highly promising delivery vehicle for the targeted therapy of AP. Inflammation-Targeted Delivery of Celastrol via Neutrophil Membrane-Coated Nanoparticles in the Management of Acute Pancreatitis Molecular PharmaceuticsAuthor: Xu Zhou, Xi Cao, He Tu, Zhi-Rong Zhang, Li Deng
https://www.nature.com/articles/nbt.4195
Oct 01, 2018 · Anti-PD-1 secreted by CAR-T cells remains localized to the tumor and improves therapeutic outcome in mice. The efficacy of chimeric antigen receptor (CAR) T cell therapy against poorly responding ...Author: Sarwish Rafiq, Oladapo O Yeku, Hollie J Jackson, Terence J Purdon, Dayenne G van Leeuwen, Dylan J Dr...
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