Targeting Bacteriophage To Mammalian Cell Surface Receptors For Gene Delivery

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Targeting bacteriophage to mammalian cell surface ...

    https://www.ncbi.nlm.nih.gov/pubmed/9829538
    Nov 01, 1998 · Targeting bacteriophage to mammalian cell surface receptors for gene delivery. Larocca D(1), Witte A, Johnson W, Pierce GF, Baird A. Author information: (1)Selective Genetics, Inc., San Diego, CA 92121, USA.Author: David Larocca, Alison Witte, Wendy Johnson, Glenn F. Pierce, Andrew Baird

Targeting Bacteriophage to Mammalian Cell Surface ...

    https://www.liebertpub.com/doi/10.1089/hum.1998.9.16-2393
    Targeting Bacteriophage to Mammalian Cell Surface Receptors for Gene Delivery. David Larocca; ... In an effort to develop novel methods for ligand discovery via phage gene delivery, we conferred mammalian cell tropism to filamentous bacteriophages by attaching basic fibroblast growth factor (FGF2), transferrin, or epidermal growth factor (EGF ...Author: David Larocca, Alison Witte, Wendy Johnson, Glenn F. Pierce, Andrew Baird

Hybrid Nanomaterial Complexes for Advanced Phage ... - Cell

    https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(16)30324-9
    Jan 01, 2014 · We hypothesized that chemical modification of the bacteriophage capsid could be applied to improve targeted gene delivery by phage vectors into mammalian cells. ... Targeting bacteriophage to mammalian cell surface receptors for gene delivery. Hum Gene Ther. 1998 ... Targeting bacteriophage to mammalian cell surface receptors for gene delivery. ...Author: Teerapong Yata, Koon-Yang Lee, Tararaj Dharakul, Sirirurg Songsivilai, Alexander Bismarck, Paul J Mi...

Bacteriophage: From Bacteria to a Successful Targeted ...

    https://www.sciencedirect.com/science/article/pii/B9780123942951000330
    In order to obtain the ideal gene delivery vector system, several attempts have been made to combine the attributes of two or more different types of vectors. In 2006, Hajitou and colleagues combined the advantages of two gene delivery vehicles, namely M13-derived fUSE5 filamentous bacteriophage and recombinant rAAV genome.Author: Teerapong Yata, Nastasia Nianiaris, Sirirurg Songsivilai, Amin Hajitou

Targeted gene delivery to mammalian cells by filamentous ...

    https://www.sciencedirect.com/science/article/pii/S0022283699926785
    All of these approaches depend on the use of targeting molecules that bind a cell-surface receptor, resulting in internalization of the gene delivery vehicle with subsequent delivery of the DNA to the nucleus. Identification of appropriate targeting molecules has largely been performed by individually screening receptor ligands or antibodies.Author: Marie-Alix Poul, James D Marks

In vivo gene delivery and expression by bacteriophage ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063594/
    Mar 13, 2006 · Bacteriophage vectors have potential as gene transfer and vaccine delivery vectors because of their low cost, safety and physical stability. However, little is known concerning phage-mediated gene transfer in mammalian hosts. We therefore performed experiments to examine phage-mediated gene transfer in vivo.Author: H.A. Lankes, C.N. Zanghi, K. Santos, C. Capella, C.M.P. Duke, S. Dewhurst

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