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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453494/
Dec 01, 2016 · A lthough drug delivery targeted to the eye is in widespread use, targeting drug delivery within the eye has received less attention. Indeed, topical eye drops generally target the anterior segment and intravitreal injections target the posterior segment, but diseases are usually more localized within these regions of the eye.Author: R PatelSamirkumar, R PrausnitzMark
https://www.cancer.org/cancer/eye-cancer/treating/targeted-therapy.html
Aug 15, 2018 · Targeted Drugs and Immunotherapy for Eye Cancer Melanoma that has spread outside of the eye can be hard to treat, and unfortunately standard chemotherapy drugs often are not very helpful. In recent years, researchers have developed newer types of drugs to treat …
https://www.researchgate.net/publication/226901243_Targeted_Drug_Delivery_to_the_Eye_Enabled_by_Microneedles
Targeted Drug Delivery to the Eye Enabled by Microneedles. Drug delivery targeted to specific tissues within the eye represents an important advance over conventional methods of topical and injectable delivery that have poor specificity for particular ocular tissues requiring therapy.
https://www.uef.fi/en/web/farmasia/targeted-drug-delivery-ocular-drug-development-
Targeted drug delivery refers to the delivery of drugs to specific targets and to the targeting of effects at specific tissues. This field plays a major role in drug development, especially when enhancing the effect of biological drugs and when delivering drugs to targets that are difficult to reach, for example the back of the eye, the brain and tumours.
https://www.sciencedirect.com/science/article/pii/S1569259005100123
One of the major challenges in ocular drug delivery has been to deliver drugs to the anterior and posterior chambers of the eye using topical dosage forms. The main disadvantages are related to the facts that the drug is diluted and washed off almost immediately due to a high tear turnover rate.Author: Ashim K. Mitra, Banmeet S. Anand, Sridhar Duvvuri
https://ieeexplore.ieee.org/document/8481386/
Abstract: We present a new optimization method for permanent magnet systems for magnetic targeted drug delivery. On the example of a human eye, special attention is paid to the challenging situation, where the placement of magnets in close vicinity of the targeted area is impossible.Author: Sergey Erokhin, Dmitry Berkov
https://www.sciencedirect.com/science/article/pii/S1359644618305117
Other than systemic administration, liposomes can also be used for direct drug delivery to the eye using intravitreal injection . This approach was, for instance, used for the encapsulation of recoverin – a protein important for the phototransduction cascade in photoreceptors.Author: Erico Himawan, Per Ekström, Matej Buzgo, Pieter Gaillard, Einar Stefánsson, Valeria Marigo, Thorstei...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · COLLOIDAL DOSAGE FORMS FOR OCULAR DRUG DELIVERY. Colloidal dosage forms have been widely studied and employed in the field of ocular drug delivery . These dosage forms include liposomes, nanoparticles, microemulsions, and nanoemulsions etc. Barriers to ocular drug delivery have already been described earlier in the context of structure and function of various ocular …Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …
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