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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815202/
This review summarized the current progress on targeted drug delivery in pancreatic cancer including the therapeutic agents, vehicles, delivery routes, and targets for specific delivery to pancreas, and provides important information on new strategies for pancreatic cancer treatment.
https://www.sciencedirect.com/science/article/pii/S0304419X09000729
This review summarizes the current progress on targeted drug delivery in pancreatic cancer including the therapeutic agents, vehicles, delivery routes, and targets for specific delivery to pancreas and provides important information on new strategies for pancreatic cancer treatment. 2. Therapeutic agentsAuthor: Xianjun Yu, Yuqing Zhang, Changyi Chen, Qizhi Yao, Min Li
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108334/
Aug 20, 2018 · Smart nanoparticles. NP drug-delivery systems that can release the drug in response to specific physiological triggers, at the appropriate time, and at the correct target site are referred to as smart NPs.11 For this review, smart NPs refer to those incorporating all three delivery strategies: passive, active, and stimuli-responsive targeting,6 as summarized in Figure 1.Author: Regina-Veronicka Kalaydina, Komal Bajwa, Bessi Qorri, Alexandria Decarlo, Myron R Szewczuk
https://www.sciencedirect.com/science/article/pii/S2211383518305653
To improve pancreas-specific drug accumulation, the neutrophil membrane-coating strategy may render therapeutic nanoparticles neutrophil-like properties such as extravasation from blood vessels to the site of tissue injury and chemokine-driven adhesion which may greatly benefit targeted drug delivery to the pancreas.Author: Xi Cao, Ying Hu, Shi Luo, Yuejing Wang, Tao Gong, Xun Sun, Yao Fu, Zhirong Zhang
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · There is no drug accumulation in healthy pancreas, ... and targeted drug delivery 132,133,134. The large surface-to-volume ratio of nanoparticles and their size, ability to …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(18)30130-6
Sep 07, 2018 · Gemcitabine-Incorporated G-Quadruplex Aptamer for Targeted Drug Delivery into Pancreas Cancer. Previous Article Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification.Author: Jun Young Park, Ye Lim Cho, Ju Ri Chae, Sung Hwan Moon, Won Gil Cho, Yun Jung Choi, Soo Jin Lee, Won...
http://grantcenter.jdrf.org/wp-content/uploads/2020/01/FY20-Targeting-RFA.pdf
Targeted drug delivery presents an opportunity to restrict a regenerative or survival therapy to the islet/beta cell and avoid or reduce on target but deleterious effects on tissues or cells outside the pancreas. Targeted drug delivery, also known as smart drug delivery, has most notably been successful in the cancer setting.
https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
Nov 09, 2012 · In view of the recognized importance of targeted drug delivery strategies for cancer therapy, we discuss the advantages of alternative drug carriers and where these should be applied, focusing on peptide-drug conjugates (PDCs), particularly …Author: Michael A Firer, Gary Gellerman
https://jtultrasound.biomedcentral.com/articles/10.1186/2050-5736-1-10
Jul 01, 2013 · Ultrasound-targeted microbubble destruction (UTMD) is a promising technique for non-invasive, targeted drug delivery, and its applications in chemotherapeutic drug delivery to solid tumors have attracted growing interest. Ultrasound, which has been conventionally used for diagnostic imaging, has evolved as a promising tool for therapeutic applications mainly because of its ability to be ...Author: Hong Chen, Joo Ha Hwang
https://www.researchgate.net/publication/38033109_Targeted_Drug_Delivery_in_Pancreatic_Cancer
Targeted Drug Delivery in Pancreatic Cancer ... developed so far for anticancer drug delivery to the pancreas over a period of 20 years, from polymeric to lipidic-based nanosystems, with a ...
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